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GANT58

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843082

Background: Cell-permeable. Acts as a blocker of Hedgehog (Hh) pathway downstream of SMO and SUFU causing Gli1 nuclear accumulation. It also targets Gli-mediated gene transactivation (IC?? ~ 5 uM in SAG-stimulated Shh-L2 cells) and displays anti-proliferative… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GANT58, Biochemical
Full Product Name
GANT58
Product Gene Name
GANT58 biochemical
Product Synonym Names
2,3,4,5-Tetra(4-pyridyl)thiophene; NSC75503
Form/Format
Appearance: Yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
392.48
CAS Number
64048-12-0
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD01103196
PubChem CID
253078
Solubility/Reconstitution Instructions
DMSO (25 mM) or Ethanol (25 mM)
SMILES
C1=CN=CC=C1C2=C(SC(=C2C3=CC=NC=C3)C4=CC=NC=C4)C5=CC=NC=C5
InChi
InChI=1S/C24H16N4S/c1-9-25-10-2-17(1)21-22(18-3-11-26-12-4-18)24(20-7-15-28-16-8-20)29-23(21)19-5-13-27-14-6-19/h1-16H
InChi Key
USWLOKMMUTWFMD-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for GANT58 biochemical

Biochemicals; Enzyme Inhibitors; Sonic Hedgehog (Shh) Signaling Pathway Antagonists and Stem Cell Research Tools; Stem Cell Fate Regulators; Differentiation and Biochemicals (A-Z)

Structure of GANT58 biochemical

GANT58 Biochemical – Cat# MBS843082

Other Notes

Small volumes of GANT58 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GANT58 purchase

MBS843082 is a biochemical targeting GANT58.
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