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BAX Activator, BAM7

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843112

Background: A potent and selective BAX activator (EC?? = 3.3 muM). BAM7 directly binds at the BH3-binding site; selective for BAX over other antiapoptotic and proapoptotic proteins. BAM7 triggers in vitro BAX oligomerization, BAX-mediated pore formation and… More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BAX Activator, BAM7, Biochemical
Full Product Name
BAX Activator, BAM7
Product Synonym Names
3-Methyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]; BAM7
Form/Format
Appearance: Brown solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
405.47
CAS Number
331244-89-4
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
5754137
Solubility/Reconstitution Instructions
DMSO (~ 2 mg/ml)
SMILES
CCOC1=CC=CC=C1NN=C2C(=NN(C2=O)C3=NC(=CS3)C4=CC=CC=C4)C
InChi
InChI=1S/C21H19N5O2S/c1-3-28-18-12-8-7-11-16(18)23-24-19-14(2)25-26(20(19)27)21-22-17(13-29-21)15-9-5-4-6-10-15/h4-13,23H,3H2,1-2H3/b24-19+
InChi Key
KOCVKGYKBLJEPK-LYBHJNIJSA-N
Handling
Protect from air and light

Other Notes

Small volumes of BAX Activator, BAM7 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BAX Activator, BAM7 purchase

MBS843112 is a biochemical targeting BAX Activator, BAM7.
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