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SB-431542

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843122

Background: A potent and selective inhibitor of the TGF-beta1 receptor ALK5 (IC?? = 94 nM). It inhibits ALK4 only at higher concentrations (IC?? = 140 nM). Suppresses renewal in embryonic and induced pluripotent stem (iPS) cells and promotes their… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SB-431542, Biochemical
Full Product Name
SB-431542
Product Gene Name
SB-431542 biochemical
Product Synonym Names
4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
384.39
CAS Number
301836-41-9
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD11045982
PubChem CID
4521392
Solubility/Reconstitution Instructions
DMSO (20 mg/ml) or EtOH (2 mg/ml)
SMILES
C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
InChi
InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
InChi Key
FHYUGAJXYORMHI-UHFFFAOYSA-N
Handling
Protect from air and light

Structure of SB-431542 biochemical

SB-431542 Biochemical – Cat# MBS843122

Other Notes

Small volumes of SB-431542 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SB-431542 purchase

MBS843122 is a biochemical targeting SB-431542.
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