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Imatinib Mesylate (CGP-57148B, STI-571)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843136

Background: An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Imatinib Mesylate (CGP-57148B, STI-571), Biochemical
Full Product Name
Imatinib Mesylate (CGP-57148B, STI-571)
Product Synonym Names
CGP-57148B; STI-571
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=99% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
589.71
CAS Number
220127-57-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD04307699
PubChem CID
123596
Solubility/Reconstitution Instructions
DMSO (100 mg/ml)
SMILES
CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
InChi
InChI=1S/C29H31N7O.CH4O3S/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36;1-5(2,3)4/h3-13,18-19H,14-17,20H2,12H3,(H,32,37)(H,31,33,34);1H3,(H,2,3,4)
InChi Key
YLMAHDNUQAMNNX-UHFFFAOYSA-N
Handling
Protect from air and moisture

Other Notes

Small volumes of Imatinib Mesylate (CGP-57148B, STI-571) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Imatinib Mesylate (CGP-57148B, STI-571) purchase

MBS843136 is a biochemical targeting Imatinib Mesylate (CGP-57148B, STI-571).
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