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GSK1904529A

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843143

Background: A potent, selective, reversible and ATP-competitive inhibitor of the insulin-like growth factor-1 receptor (IGF-1R) and Insulin Receptor (IR) with IC??s of 27 and 25 nM, respectively. More details

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Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GSK1904529A, Biochemical
Full Product Name
GSK1904529A
Product Gene Name
Product Synonym Names
N-(2,6-difluorophenyl)-5-(3-(2-(5-ethyl-2-methoxy-4-(4-(4-(methylsulfonyl)piperazin-1-yl)piperidin-1-yl)phenylamino)pyrimidin-4-yl)H-imidazo[1,2-a]pyridin-2-yl)-2-methoxybenzamide
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
851.96
CAS Number
1089283-49-7
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD17010271
PubChem CID
25124816
Solubility/Reconstitution Instructions
DMSO (>100 mg/ml)
SMILES
CCC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)S(=O)(=O)C)OC)NC4=NC=CC(=N4)C5=C(N=C6N5C=CC=C6)C7=CC(=C(C=C7)OC)C(=O)NC8=C(C=CC=C8F)F
InChi
InChI=1S/C44H47F2N9O5S/c1-5-28-26-35(38(60-3)27-36(28)53-19-15-30(16-20-53)52-21-23-54(24-22-52)61(4,57)58)49-44-47-17-14-34(48-44)42-40(50-39-11-6-7-18-55(39)42)29-12-13-37(59-2)31(25-29)43(56)51-41-32(45)9-8-10-33(41)46/h6-14,17-18,25-27,30H,5,15-16,19-24H2,1-4H3,(H,51,56)(H,47,48,49)
InChi Key
MOSKATHMXWSZTQ-UHFFFAOYSA-N
Handling
Protect from light and moisture

Other Notes

Small volumes of GSK1904529A biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK1904529A purchase

MBS843143 is a biochemical targeting GSK1904529A.
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