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CFTR Inhibitor, GlyH-101

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843166

Background: CFTR Inhibitor II, or GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 uM). GlyH-101 binds to a site at the external pore of CFTR, occluding the pore and rapidly preventing chloride transport. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CFTR Inhibitor, GlyH-101, Biochemical
Full Product Name
CFTR Inhibitor, GlyH-101
Product Synonym Names
2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide N-2-naphthalenyl-glycine; GlyH-101; Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor II
Form/Format
Appearance: Yellow solid
Purity/Purification
>=98%
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
493.15
CAS Number
328541-79-3
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD01532954
PubChem CID
11260414
Solubility/Reconstitution Instructions
DMSO (>100 mg/ml)
SMILES
C1=CC=C2C=C(C=CC2=C1)NCC(=O)NNC=C3C=C(C(=C(C3=O)Br)O)Br
InChi
InChI=1S/C19H15Br2N3O3/c20-15-8-13(18(26)17(21)19(15)27)9-23-24-16(25)10-22-14-6-5-11-3-1-2-4-12(11)7-14/h1-9,22-23,27H,10H2,(H,24,25)/b13-9-
InChi Key
FLGYCSPPJQJZCH-LCYFTJDESA-N
Handling
Protect from air and light

Product Categories/Family for CFTR Inhibitor, GlyH-101 biochemical

Enzyme Inhibitors; Other Inhibitors; Other InhibitorsEnzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Enzyme Inhibitors; Other InhibitorsBiochemicals; Enzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Biochemicals (A-Z)

Structure of CFTR Inhibitor, GlyH-101 biochemical

CFTR Inhibitor, GlyH-101 Biochemical – Cat# MBS843166

Other Notes

Small volumes of CFTR Inhibitor, GlyH-101 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CFTR Inhibitor, GlyH-101 purchase

MBS843166 is a biochemical targeting CFTR Inhibitor, GlyH-101.
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