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TMP269

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843167

Background: TMP269 is a potent, selective and cell-permeable class IIa HDAC inhibitor (IC?? values of of 126 nM, 80 nM, 36 nM and 19 nM for HDAC4, HDAC5, HDAC7 and HDAC9 respectively). Displays 20-400 fold selectivity over class I HDACs. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TMP269, Biochemical
Full Product Name
TMP269
Product Gene Name
TMP269 biochemical
Product Synonym Names
N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide; TMP-269
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
514.52
CAS Number
1314890-29-3
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
Solubility/Reconstitution Instructions
DMSO (>25 mg/ml)
SMILES
O=C(NCC1(C2=NC(C3=CC=CC=C3)=CS2)CCOCC1)C4=CC=CC(C5=NOC(C(F)(F)F)=N5)=C4
InChi
InChI=1S/C25H21F3N4O3S/c26-25(27,28)22-31-20(32-35-22)17-7-4-8-18(13-17)21(33)29-15-24(9-11-34-12-10-24)23-30-19(14-36-23)16-5-2-1-3-6-16/h1-8,13-14H,9-12,15H2,(H,29,33)
InChi Key
HORXBWNTEDOVKN-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for TMP269 biochemical

Enzyme Inhibitors; Histone Deacetylase (HDAC) InhibitorsBiochemicals; Enzyme Inhibitors; Histone Deacetylase (HDAC) InhibitorsEpigenetics; Eraser Enzymes; Histone Deacetylases; HDAC InhibitorsEpigenetics; Epigenetic Modulators (A-Z) Biochemicals; Biochemi

Structure of TMP269 biochemical

TMP269 Biochemical – Cat# MBS843167

Other Notes

Small volumes of TMP269 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMP269 purchase

MBS843167 is a biochemical targeting TMP269.
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