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Ki 8751

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843175

Background: Ki 8751 is a potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC?? = 0.9 nM). It is >40-fold selective for VEGFR2 than c-Kit, PDGFRalpha and FGFR-2, little activity to EGFR, HGFR and InsR. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Ki 8751, Biochemical
Full Product Name
Ki 8751
Product Gene Name
Ki 8751 biochemical
Product Synonym Names
N-(2,4-Difluorophenyl)-N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
469.41
CAS Number
228559-41-9
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD09971092
PubChem CID
11317348
Solubility/Reconstitution Instructions
DMSO (>40 mg/ml)
SMILES
 COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC(=C(C=C3)NC(=O)NC4=C(C=C(C=C4)F)F)F
InChi
 InChI=1S/C24H18F3N3O4/c1-32-22-11-15-20(12-23(22)33-2)28-8-7-21(15)34-14-4-6-19(17(27)10-14)30-24(31)29-18-5-3-13(25)9-16(18)26/h3-12H,1-2H3,(H2,29,30,31)
InChi Key
LFKQSJNCVRGFCC-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for Ki 8751 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsBiochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsBiochemicals; Biochemicals (A-Z)

Structure of Ki 8751 biochemical

Ki 8751 Biochemical – Cat# MBS843175

Other Notes

Small volumes of Ki 8751 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ki 8751 purchase

MBS843175 is a biochemical targeting Ki 8751.
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