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AZD-3463

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843190

Background: AZD-3463 is a potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor that displays ability to overcome acquired resistance to Crizotinib. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AZD-3463, Biochemical
Full Product Name
AZD-3463
Product Gene Name
AZD-3463 biochemical
Product Synonym Names
2-Pyrimidinamine; N-[4-(4-amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
448.95
CAS Number
1356962-20-3
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
56599293
Solubility/Reconstitution Instructions
DMSO (~20 mg/ml)
SMILES
COC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
InChi
InChI=1S/C24H25ClN6O/c1-32-22-12-16(31-10-8-15(26)9-11-31)6-7-21(22)29-24-28-14-19(25)23(30-24)18-13-27-20-5-3-2-4-17(18)20/h2-7,12-15,27H,8-11,26H2,1H3,(H,28,29,30)
InChi Key
GCYIGMXOIWJGBU-UHFFFAOYSA-N
Handling
Protect from light and moisture

Product Categories/Family for AZD-3463 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of AZD-3463 biochemical

AZD-3463 Biochemical – Cat# MBS843190

Other Notes

Small volumes of AZD-3463 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD-3463 purchase

MBS843190 is a biochemical targeting AZD-3463.
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