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AZ10417808

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843223

Background: AZ10417808 is a selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 muM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AZ10417808, Biochemical
Full Product Name
AZ10417808
Product Gene Name
AZ10417808 biochemical
Product Synonym Names
2-(3,4-dichloroanilino)-6-nitro-4-oxo-N-prop-2-enyl-1H-quinazoline-8-carboxamide
Form/Format
Appearance: Yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
434.23
CAS Number
331645-84-2
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Y
PubChem CID
16759160
Solubility/Reconstitution Instructions
DMSO (~ 10 mg/ml)
SMILES
C=CCNC(=O)C1=C2C(=CC(=C1)[N+](=O)[O-])C(=O)N=C(N2)NC3=CC(=C(C=C3)Cl)Cl
InChi
InChI=1S/C18H13Cl2N5O4/c1-2-5-21-16(26)11-7-10(25(28)29)8-12-15(11)23-18(24-17(12)27)22-9-3-4-13(19)14(20)6-9/h2-4,6-8H,1,5H2,(H,21,26)(H2,22,23,24,27)
InChi Key
VUBILPOZTRGZJK-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for AZ10417808 biochemical

Enzyme Inhibitors; Caspase & Granzyme B InhibitorsBiochemicals; Enzyme Inhibitors; Caspase & Granzyme B InhibitorsApoptosis & Related Products; Caspase Inhibitors; Caspase InhibitorsBiochemicals; Biochemicals (A-Z)

Structure of AZ10417808 biochemical

AZ10417808 Biochemical – Cat# MBS843223

Other Notes

Small volumes of AZ10417808 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZ10417808 purchase

MBS843223 is a biochemical targeting AZ10417808.
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