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SB-715992

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843236

Background: A potent, reversible, small molecule inhibitor of kinesin spindle protein (KSP), a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis. Displays anticancer properties. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SB-715992, Biochemical
Full Product Name
SB-715992
Product Gene Name
SB-715992 biochemical
Product Synonym Names
(R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamide; Ispinesib; CK0238273
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
517.06
CAS Number
336113-53-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
6851740
Solubility/Reconstitution Instructions
DMSO (> 50 mg/ml)
SMILES
CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C
InChi
InChI=1S/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1
InChi Key
QJZRFPJCWMNVAV-HHHXNRCGSA-N
Handling
Protect from air and light

Product Categories/Family for SB-715992 biochemical

Enzyme Inhibitors; Other Inhibitors; Other Inhibitors and Biochemicals; Enzyme Inhibitors; Other Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of SB-715992 biochemical

SB-715992 Biochemical – Cat# MBS843236

Other Notes

Small volumes of SB-715992 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SB-715992 purchase

MBS843236 is a biochemical targeting SB-715992.
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