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UNC0631

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843253

Background: UNC0631 is a potent and selective inhibitor of G9a activity in vitro (IC?? = 4 nM) and G9a/GLP-mediated dimethylation of histone 3 on lysine 9 in MDA-MB-231 cells (IC?? = 25 nM). It potently inhibits G9a/GLP activity in a variety of cancer cell… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
UNC0631, Biochemical
Full Product Name
UNC0631
Product Gene Name
UNC0631 biochemical
Product Synonym Names
[N-(1-(cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine
Form/Format
Appearance: White to off-white solid
Purity/Purification
>98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
635.93
CAS Number
1320288-19-4
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
Solubility/Reconstitution Instructions
DMSO (~30 mg/ml)
SMILES
CC(C)N(CC1)CCCN1C2=NC(C=C(OCCCN(C)CC)C(OC)=C3)=C3C(NC(CC4)CCN4CC5CCCCC5)=N2
InChi
InChI=1S/C35H59N7O2/c1-6-39(4)16-11-23-44-33-25-31-30(24-32(33)43-5)34(38-35(37-31)42-18-10-17-41(21-22-42)27(2)3)36-29-14-19-40(20-15-29)26-28-12-8-7-9-13-28/h24-25,27-29H,6-23,26H2,1-5H3,(H,36,37,38)
InChi Key
GJFNQXAYZZYAQU-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for UNC0631 biochemical

Enzyme Inhibitors; Methyltransferase Inhibitors and Biochemicals; Enzyme Inhibitors; Methyltransferase Inhibitors and Epigenetics; Writer Enzymes; Protein Lysine Methyltransferases (PKMTs); PKMT Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of UNC0631 biochemical

UNC0631 Biochemical – Cat# MBS843253

Other Notes

Small volumes of UNC0631 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UNC0631 purchase

MBS843253 is a biochemical targeting UNC0631.
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