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Sphingosine Kinase Inhibitor, SKI-I

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843298

Background: Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Sphingosine Kinase Inhibitor, SKI-I, Biochemical
Full Product Name
Sphingosine Kinase Inhibitor, SKI-I
Product Synonym Names
5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide
Form/Format
Appearance: Pale yellow solid
Purity/Purification
>=90% by NMR
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
406.44
CAS Number
306301-68-8
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
Solubility/Reconstitution Instructions
DMSO
SMILES
O=C(N/N=C/C1C2CCCCC2CCC1O)C3CC(NN3)C4CCC5CCCCC5C4
InChi
InChI=1S/C25H18N4O2/c30-24-12-11-17-6-3-4-8-20(17)21(24)15-26-29-25(31)23-14-22(27-28-23)19-10-9-16-5-1-2-7-18(16)13-19/h1-15,30H,(H,27,28)(H,29,31)/b26-15+
InChi Key
XOXCTLAKMCIWCF-CVKSISIWSA-N
Handling
Protect from air and light

Product Categories/Family for Sphingosine Kinase Inhibitor, SKI-I biochemical

Biochemicals; Enzyme Inhibitors; Sphingosine Kinase (SK) Inhibitors and Biochemicals (A-Z)

Structure of Sphingosine Kinase Inhibitor, SKI-I biochemical

Sphingosine Kinase Inhibitor, SKI-I Biochemical – Cat# MBS843298

Other Notes

Small volumes of Sphingosine Kinase Inhibitor, SKI-I biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sphingosine Kinase Inhibitor, SKI-I purchase

MBS843298 is a biochemical targeting Sphingosine Kinase Inhibitor, SKI-I.
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