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ONX-0914

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843299

Background: A potent and selective immunoproteasome inhibitor with minimal cross-reactivity for the constitutive proteasome. It selectively inhibits low-molecular mass polypeptide-7 (LMP7, encoded by Psmb8), the chymotrypsin-like subunit of the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ONX-0914, Biochemical
Full Product Name
ONX-0914
Product Gene Name
ONX-0914 biochemical
Product Synonym Names
(S)-3-(4-methoxyphenyl)-N-((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)propanamido)propanamide; PR-957
Form/Format
Appearance: White olid
Purity/Purification
>=95% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
580.67
CAS Number
960374-59-8
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
59254457
Solubility/Reconstitution Instructions
DMSO (>50 mg/ml)
SMILES
CC(C(=O)NC(CC1=CC=C(C=C1)OC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)C)NC(=O)CN4CCOCC4
InChi
InChI=1S/C31H40N4O7/c1-21(32-27(36)19-35-13-15-41-16-14-35)29(38)34-26(18-23-9-11-24(40-3)12-10-23)30(39)33-25(28(37)31(2)20-42-31)17-22-7-5-4-6-8-22/h4-12,21,25-26H,13-20H2,1-3H3,(H,32,36)(H,33,39)(H,34,38)/t21-,25-,26-,31?/m0/s1
InChi Key
WQAVPPWWLLVGFK-ZCKRSBOQSA-N
Handling
Protect from air and light

Product Categories/Family for ONX-0914 biochemical

Enzyme Inhibitors; Proteasome Inhibitors and Biochemicals; Enzyme Inhibitors; Proteasome Inhibitors and Enzyme Inhibitors; Ubiquitin Proteasome Pathway Inhibitors and Biochemicals; Enzyme Inhibitors; Ubiquitin Proteasome Pathway Inhibitors and Signaling P

Structure of ONX-0914 biochemical

ONX-0914 Biochemical – Cat# MBS843299

Other Notes

Small volumes of ONX-0914 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ONX-0914 purchase

MBS843299 is a biochemical targeting ONX-0914.
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