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ZM 447439

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843301

Background: Cell-permeable. A selective, ATP-competitive inhibitor of Aurora B kinase in vitro (IC?? values are 50 nM, 250 nM and 1 muM for Aurora B, C and A kinases respectively). Selective over a range of other kinases including cdk1 and PLK1 (IC?? > 10… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ZM 447439, Biochemical
Full Product Name
ZM 447439
Product Gene Name
ZM 447439 biochemical
Product Synonym Names
N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide
Form/Format
Appearance: Orange solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
513.59
CAS Number
331771-20-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD08703125
PubChem CID
9914412
Solubility/Reconstitution Instructions
DMSO (100 mM)
SMILES
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5
InChi
InChI=1S/C29H31N5O4/c1-36-26-18-24-25(19-27(26)38-15-5-12-34-13-16-37-17-14-34)30-20-31-28(24)32-22-8-10-23(11-9-22)33-29(35)21-6-3-2-4-7-21/h2-4,6-11,18-20H,5,12-17H2,1H3,(H,33,35)(H,30,31,32)
InChi Key
OGNYUTNQZVRGMN-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for ZM 447439 biochemical

Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Aurora Kinase Inhibitors and Biochemicals (A-Z)

Structure of ZM 447439 biochemical

ZM 447439 Biochemical – Cat# MBS843301

Other Notes

Small volumes of ZM 447439 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZM 447439 purchase

MBS843301 is a biochemical targeting ZM 447439.
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