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Cyt387

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843305

Background: Cyt387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC?? values of 11 nM and 18 nM, respectively. Inhibits JAK3 at much higher concentrations (IC?? = 155 nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Cyt387, Biochemical
Full Product Name
Cyt387
Product Gene Name
Cyt387 biochemical
Product Synonym Names
(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-l)-benzamide; CYT11387
Form/Format
Appearance: Yellow to light orange solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
414.46
CAS Number
1056634-68-4
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD16038899
PubChem CID
25062766
Solubility/Reconstitution Instructions
DMSO (~80 mg/ml) or Ethanol (<1 mg/ml)
SMILES
C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N
InChi
InChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27,28)
InChi Key
ZVHNDZWQTBEVRY-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for Cyt387 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; JAK Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; JAK Inhibitors and Epigenetics; Writer Enzymes; Kinases; Kinase Inhibitors; JAK2 Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of Cyt387 biochemical

CYT387 Biochemical – Cat# MBS843305

Other Notes

Small volumes of Cyt387 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cyt387 purchase

MBS843305 is a biochemical targeting Cyt387.
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