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GDC-0068

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843316

Background: GDC-0068 is a potent, ATP-competitive, pan-Akt inhibitor with IC??s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively. Displays selectivity over more than other 200 screened kinases. Potential anticancer agent. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GDC-0068, Biochemical
Full Product Name
GDC-0068
Product Gene Name
GDC-0068 biochemical
Product Synonym Names
(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
458
CAS Number
1001264-89-6
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
24788740
Solubility/Reconstitution Instructions
DMSO (>50 mg/ml)
SMILES
CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O
InChi
nChI=1S/C24H32ClN5O2/c1-15(2)26-13-19(17-4-6-18(25)7-5-17)24(32)30-10-8-29(9-11-30)23-21-16(3)12-20(31)22(21)27-14-28-23/h4-7,14-16,19-20,26,31H,8-13H2,1-3H3/t16-,19-,20-/m1/s1
InChi Key
GRZXWCHAXNAUHY-NSISKUIASA-N
Handling
Protect from air and light

Product Categories/Family for GDC-0068 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Akt InhibitorsBiochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Akt InhibitorsSignaling Pathways; PI3 K/Akt/mTOR Signaling; Inhibitors; Akt InhibitorsBiochemicals; Biochemicals (A-Z)

Structure of GDC-0068 biochemical

GDC-0068 Biochemical – Cat# MBS843316

Other Notes

Small volumes of GDC-0068 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDC-0068 purchase

MBS843316 is a biochemical targeting GDC-0068.
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