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Hemopexin (HPX) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8120533

MBS8120533 is an active protein targeting HPX. Also known as Hemopexin Protein, Human, Recombinant (His Tag). Host: HEK293 Cells. More details

$415 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Hemopexin (HPX), Active Protein
Full Product Name
Hemopexin Protein, Human, Recombinant (His Tag)
Product Gene Name
Product Synonym Names
Human Hemopexin/HPX Protein (His Tag); HX Protein, Human; hemopexin
Host
HEK293 Cells
Form/Format
Lyophilized from sterile PBS, pH7.4. 5% trehalose, 5% mannitol and 0.01% Tween80
Purity/Purification
>96% as determined by SDS-PAGE
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended to aliquot the protein into smaller quantities for optimal storage.
Chromosome Location
Chromosome: 11; NC_000011.9 (6452268..6462254, complement). Location: 11p15.5-p15.4
OMIM
142290
3D Structure
ModBase 3D Structure for P02790
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Species
Human
Bio Activity
Measured by its ability to bind protoporphyrin IX (PPPIX). Recombinant human Hemopexin binds >10 uM PPPIX, resulting in a 50% decrease in the fluorescence signal of human Hemopexin.
Endotoxin
<1.0EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Thr 24
Tag
His Tag
Protein Construction
A DNA sequence encoding the human HPX (NP_000604.1)(Met 1-His 462) with a C-terminal polyhistidine tag was expressed.
Reconstitution
It is recommeneded that sterile water (400ul) be added to the vial to prepare a stock solution of 0.25mg/mL. Concentration is mesured by UV.

SDS-Page of HPX active protein

HPX Active Protein – Cat# MBS8120533

Other Notes

Small volumes of HPX active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HPX. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
hemopexin
NCBI Official Synonym Full Names
hemopexin
NCBI Official Symbol
HPX
NCBI Official Synonym Symbols
HX
UniProt Protein Name
Hemopexin
UniProt Synonym Protein Names
Beta-1B-glycoprotein
Protein Family
UniProt Gene Name
HPX
UniProt Entry Name
HEMO_HUMAN
NCBI Protein Information
hemopexin; beta-1B-glycoprotein

NCBI Summary for HPX

This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. [provided by RefSeq, Apr 2009]

UniProt Comments for HPX

HPX: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Belongs to the hemopexin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11p15.5-p15.4

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; metal ion binding; heme transporter activity

Biological Process: positive regulation of humoral immune response mediated by circulating immunoglobulin; receptor-mediated endocytosis; positive regulation of immunoglobulin production; heme transport; positive regulation of tyrosine phosphorylation of Stat1 protein; viral reproduction; hemoglobin metabolic process; cellular iron ion homeostasis; heme metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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