Histone Protein (H2BFS) Protein

Name: H2BFS Protein; Histone Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS844094
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844094

Background: Native histones isolated from calf thymus. A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4. The… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Histone Protein (H2BFS), Protein

Full Product Name

Histone Protein

Product Gene Name

H2BFS protein

Product Synonym Names

Histone Protein; histone

Host

Calf thymus

Form/Format

Lyophilized powder
Appearance: Lyophilized powder

Concentration

10 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

13,944 Da

Handling

Centrifuge the vial prior to opening.

Product Categories/Family for H2BFS protein

Epigenetics; Histones; Recombinant ProteinsEpigenetics; Recombinant ProteinsProteins and Enzymes; Native Proteins Proteins and Enzymes; Animal-Free Origin (AOF) Recombinant Proteins & EnzymesProteins and Enzymes; Proteins and Enzymes (A-Z)

Applications Tested/Suitable for H2BFS protein

SDS-PAGE; HPLC

Other Notes

Small volumes of H2BFS protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for H2BFS purchase

MBS844094 is a protein targeting H2BFS. Also known as Histone Protein. Host: Calf thymus.

Additional Details

NCBI/Uniprot data below describe general gene information for H2BFS. It may not necessarily be applicable to this product.

NCBI GI #

56377667

NCBI GeneID

54145

NCBI Accession #

BAD74065.1

UniProt Secondary Accession #

Q5R2W0; A0AVF9

UniProt Related Accession #

P57053

NCBI Official Full Name

histone protein

NCBI Official Synonym Full Names

H2B histone family, member S (pseudogene)

NCBI Official Symbol

H2BFS

UniProt Protein Name

Histone H2B type F-S

UniProt Synonym Protein Names

Histone H2B.s; H2B/s

Protein Family

Histone

UniProt Gene Name

H2BFS

UniProt Synonym Gene Names

H2B/s

UniProt Entry Name

H2BFS_HUMAN

UniProt Comments for H2BFS

H2BFS: a core component of the nucleoosome. The nucleosome, a basic organizational unit of chromosomal DNA, is octrameric, consisting of two molecules each of histones H2B, H2A, H3, H4. The octamer wraps approximately 147 bp of DNA. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: extracellular space; nucleosome; nucleus

Molecular Function: DNA binding; protein heterodimerization activity

Biological Process: defense response to Gram-positive bacterium; substantia nigra development; innate immune response in mucosa; antibacterial humoral response

Research Articles on H2BFS

1. The H2BFS promoter is activated by serum depletion according to promoter reporter assays in HEK 293 cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.