Caspase-10/B Recombinant Protein

Background: Caspase-10b (also known as FLICE 2) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-10 also exists in cells as an inactive proenzyme. During apoptosis procaspase-10 is processed at aspartate residues to form active caspase-10 which consists of two large (18 kDa) and two small (11 kDa) subunits in a heterotetramer form. The recombinant active human caspase-10/b was expressed in E. coli. The active caspase-10 is routinely tested at MyBioSource for its ability to enzymatically cleave these two substrates Ac-IETD-pNA or Ac-IETD-AFC (1062-200).

Small volumes of Caspase-10/b recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS844126 is a recombinant protein targeting Caspase-10/b. Also known as Caspase-10 / b, human recombinant. Host: E Coli.