FIBP Recombinant Protein

Name: FIBP Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS844165
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844165

Background: Acidic fibroblast growth factor intracellular-binding protein isoform a, also known as FIBP, is a member of Fibroblast growth factors (FGFs) represent a family. FGF activity influences development, adult tissue homeostasis, angiogenesis and cancer… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

FIBP, Recombinant Protein

Full Product Name

FIBP, human recombinant

Product Gene Name

FIBP recombinant protein

Product Synonym Names

Acidic fibroblast growth factor intracellular-binding protein; FGFIBP; FIBP-1

Sequence

MGSSHHHHHH SSGLVPRGSH MGSMTSELDI FVGNTTLIDE DVYRLWLDGY SVTDAVALRV RSGILEQTGA TAAVLQSDTM DHYRTFHMLE RLLHAPPKLL HQLIFQIPPS RQALLIERYY AFDEAFVREV LGKKLSKGTK KDLDDISTKT GITLKSCRRQ FDNFKRVFKV VEEMRGSLVD NIQQHFLLSD RLARDYAAIV FFANNRFETG KKKLQYLSFG DFAFCAELMI QNWTLGAVGE APTDPDSQMD DMDMDLDKEF LQDLKELKVL VADKDLLDLH KSLVCTALRG KLGVFSEMEA NFKNLSRGLV NVAAKLTHNK DVRDLFVDLV EKFVEPCRSD HWPLSDVRFF LNQYSASVHS LDGFRHQALW DRYMGTLRGC LLRLYHD

Host

E Coli

Form/Format

0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Appearance: Liquid

Purity/Purification

>=95%

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -80 degree C
Shelf Life: 12 months

Molecular Weight

44.3 kDa (387 aa, 1-364 aa + His Tag), confirmed by MALDI-TOF.

OMIM

608296

3D Structure

ModBase 3D Structure for O43427

Handling

Centrifuge the vial prior to opening.

Product Categories/Family for FIBP recombinant protein

Cytokines; Growth Factors & Hormones; FGFsCytokines; Growth Factors & Hormones; Cytokines & Growth Factors (A-Z) Proteins and Enzymes; Cytokines; Growth Factors & Hormones; FGFsProteins and Enzymes; Cytokines; Growth Factors & Hormones; Cytokines & Growth

Applications Tested/Suitable for FIBP recombinant protein

SDS-PAGE

Other Notes

Small volumes of FIBP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FIBP purchase

MBS844165 is a recombinant protein targeting FIBP. Also known as FIBP, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for FIBP. It may not necessarily be applicable to this product.

NCBI GI #

7262378

NCBI GeneID

9158

NCBI Accession #

NP_004205.2

UniProt Primary Accession #

O43427

UniProt Secondary Accession #

Q27Q85; Q6IBQ3; Q9HD65; A8K0J7

UniProt Related Accession #

O43427

GenBank Nucleotide #

NM_004214.4

NCBI Official Full Name

acidic fibroblast growth factor intracellular-binding protein isoform b

NCBI Official Synonym Full Names

fibroblast growth factor (acidic) intracellular binding protein

NCBI Official Symbol

FIBP

NCBI Official Synonym Symbols

FGFIBP; FIBP-1

UniProt Protein Name

Acidic fibroblast growth factor intracellular-binding protein

UniProt Synonym Protein Names

FGF-1 intracellular-binding protein

Protein Family

Acidic fibroblast growth factor intracellular-binding protein

UniProt Gene Name

FIBP

UniProt Synonym Gene Names

aFGF intracellular-binding protein

UniProt Entry Name

FIBP_HUMAN

NCBI Protein Information

acidic fibroblast growth factor intracellular-binding protein

NCBI Summary for FIBP

Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for FIBP

FIBP: May be involved in mitogenic function of FGF1. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: nucleoplasm; mitochondrion; membrane; endomembrane system; nucleus

Molecular Function: fibroblast growth factor binding

Biological Process: fibroblast growth factor receptor signaling pathway

Research Articles on FIBP

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FIBP recombinant protein

Reference Product	PubMed Publications
FGF1 recombinant protein	>2 publications with FIBP and FGF1
FGFBP1 recombinant protein	>1 publications with FIBP and FGFBP1
CDK5 recombinant protein	>1 publications with FIBP and CDK5

Diseases associated with FIBP recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>2 publications with FIBP and Nervous System Diseases
Atrophy Antibodies	>1 publications with FIBP and Atrophy

Organs/Tissues associated with FIBP recombinant protein

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>1 publications with FIBP and Vascular
Lymph Node Antibodies	>1 publications with FIBP and Lymph Node
Ear Antibodies	>1 publications with FIBP and Ear
Lymph Antibodies	>1 publications with FIBP and Lymph
Larynx Antibodies	>1 publications with FIBP and Larynx
Blood Antibodies	>1 publications with FIBP and Blood
Ovary Antibodies	>1 publications with FIBP and Ovary
Embryonic Tissue Antibodies	>1 publications with FIBP and Embryonic Tissue