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Il-17a (IL17A) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844178

Background: Recombinant rat IL-17 produced from E. coli is a homodimeric, non-glycosylated polypeptide containing 268 amino acids and has a molecular weight of 30 kDa. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IL-17A (IL17A), Active Protein
Full Product Name
IL-17A, rat recombinant
Product Gene Name
Product Synonym Names
IL17A/F; IL17 A/F; IL-17A/F Interleukin-17 A/F; Interleukin-17 AF; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8.
Host
E Coli
Form/Format
Lyophilized (from 10 mM Sodium Citrate, pH 3.0).
Appearance: Lyophilized protein
Purity/Purification
>=95%
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
30 kDa
3D Structure
ModBase 3D Structure for Q61453
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Solubility/Reconstitution Instructions
Reconstitute in H?O to a concentration of 0.1-1.0 ug/ul (Note: Gently pipetting to dissolve). The solution can then be diluted into other aqueous buffers
Endotoxin Level
<0.1 ng/mug
Biological Activity
The rat IL-17 is fully biologically active when compared to standards via dose-dependent induction of IL-6 production in cultured mouse NIH 3T3 fibroblast. The ED?? for recombinant rat IL-17A in this assay was 30 ng/ml.
Results
30 ng/ ml
Handling
Centrifuge the vial prior to opening.
Applications Tested/Suitable for IL17A active protein
SDS-PAGE; HPLC

Other Notes

Small volumes of IL17A active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL17A purchase

MBS844178 is an active protein targeting IL17A. Also known as IL-17A, rat recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for IL17A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Interleukin-17A
NCBI Official Synonym Full Names
interleukin 17A
NCBI Official Symbol
Il17a
NCBI Official Synonym Symbols
Il17; IL-17; CTLA-8; IL-17A
UniProt Protein Name
Interleukin-17A
UniProt Synonym Protein Names
Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8
Protein Family
UniProt Gene Name
Il17a
UniProt Synonym Gene Names
Ctla8; Il17; IL-17; IL-17A; CTLA-8
UniProt Entry Name
IL17_RAT
NCBI Protein Information
interleukin-17A

NCBI Summary for IL17A

cytokine; may be involved in immune system function or to cell death and cell survival [RGD, Feb 2006]

UniProt Comments for IL17A

Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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