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TFF-2 (TFF2) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844191

Background: The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TFF-2 (TFF2), Active Protein
Full Product Name
TFF-2, human recombinant
Product Gene Name
Product Synonym Names
Trefoil Factor 2; Spasmolytic polypeptide (SP); Spasmolysin
Host
E Coli
Form/Format
Sterile filtered and lyophilized with no additives
Appearance: Lyophilized protein
Purity/Purification
>=98%
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
12.0 kDa
3D Structure
ModBase 3D Structure for Q03404
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Solubility/Reconstitution Instructions
Reconstitute in H?O to a concentration of 0.1-1.0 mug/mul. The solution can then be diluted into other aqueous buffers
Endotoxin Level
<0.1 ng/mug
Biological Activity
Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ug/ml.
Results
1.0-10.0 ug/ml
Handling
Centrifuge the vial prior to opening.
Applications Tested/Suitable for TFF2 active protein
SDS-PAGE; HPLC

Other Notes

Small volumes of TFF2 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TFF2 purchase

MBS844191 is an active protein targeting TFF2. Also known as TFF-2, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TFF2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
Trefoil factor 2
UniProt Protein Name
Trefoil factor 2
UniProt Synonym Protein Names
Spasmolytic polypeptide; SP
Protein Family
UniProt Gene Name
Tff2
UniProt Synonym Gene Names
Sml1; Sp; SP
UniProt Entry Name
TFF2_MOUSE

UniProt Comments for TFF2

TFF2: Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region; intracellular

Molecular Function: CXCR4 chemokine receptor binding

Biological Process: negative regulation of inflammatory response; positive regulation of cell proliferation; calcium-mediated signaling; negative regulation of macrophage activation; regulation of cell migration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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