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CIRBP/Cold-Inducible RNA-Binding Protein (CIRBP) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844239

Background: CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CIRBP/Cold-inducible RNA-binding protein, Recombinant Protein
Full Product Name
CIRBP / Cold-inducible RNA-binding protein, human recombinant
Product Gene Name
Product Synonym Names
A18HNRNP; CIRP; CIRBP
Host
E Coli
Form/Format
Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol.
Appearance: Lyophilized
Purity/Purification
>=90%
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
20.5 kDa
OMIM
602649
3D Structure
ModBase 3D Structure for Q14011
Solubility/Reconstitution Instructions
Detailed reconstitution instructions are sent along with the product
Endotoxin Level
< 1.0 EU per mug of the protein as determined by the LAL method.
Handling
Centrifuge the vial prior to opening.
Applications Tested/Suitable for CIRBP recombinant protein
SDS-PAGE

Other Notes

Small volumes of CIRBP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CIRBP purchase

MBS844239 is a recombinant protein targeting CIRBP. Also known as CIRBP / Cold-inducible RNA-binding protein, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CIRBP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cold-inducible RNA-binding protein isoform 1
NCBI Official Synonym Full Names
cold inducible RNA binding protein
NCBI Official Symbol
CIRBP
NCBI Official Synonym Symbols
CIRP
UniProt Protein Name
Cold-inducible RNA-binding protein
UniProt Synonym Protein Names
A18 hnRNP; Glycine-rich RNA-binding protein CIRP
UniProt Gene Name
CIRBP
UniProt Synonym Gene Names
A18HNRNP; CIRP
UniProt Entry Name
CIRBP_HUMAN
NCBI Protein Information
cold-inducible RNA-binding protein

UniProt Comments for CIRBP

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (). Promotes assembly of stress granules (SGs), when overexpressed.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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