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MIP-2/Gro-Beta (MIP2) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844296

Background: Murine microphage inflammatory protein-2 (MIP-2) promotes neutrophil chemotaxis and degranulation. MyBioSource's murine MIP-2 is a 7.8 kDa protein containing 73 amino acid residues including the 'RLR' motif common to the CXC chemokine family that… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MIP-2/Gro-beta (MIP2), Active Protein
Full Product Name
MIP-2 / Gro-beta, murine recombinant
Product Gene Name
Product Synonym Names
Macrophage inflammatory protein 2-alpha; MIP2-alpha; CXCL2; Growth- regulated protein beta; Gro-beta; chemokine (C-X-C motif) ligand 2; GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a; MGSA beta;
Host
E Coli
Form/Format
Sterile filtered and then lyophilized with no additives
Appearance: Lyophilized protein
Purity/Purification
>=98%
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
7.8 kDa
3D Structure
ModBase 3D Structure for P10889
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Solubility/Reconstitution Instructions
Reconstitute in H?O to a concentration of 0.1-1 mg/ml. The solution can be diluted into other aqueous buffers and store at 4 degree C for 1 week or -20 degree C for future use.
Endotoxin Level
<0.1 ng/mug
Biological Activity
Determined by measuring the dose dependent mobilization of intraCellular calcium (calcium flux) with human neutrophils. Significant calcium mobilization is observed with >5 ng/ml of recombinant mouse MIP-2.
Results
>5 ng/ml
Handling
Centrifuge the vial prior to opening.
Applications Tested/Suitable for MIP2 active protein
SDS-PAGE; HPLC

Other Notes

Small volumes of MIP2 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MIP2 purchase

MBS844296 is an active protein targeting MIP2. Also known as MIP-2 / Gro-beta, murine recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MIP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-X-C motif chemokine 2
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 2
NCBI Official Symbol
Cxcl2
NCBI Official Synonym Symbols
GROb; Gro2; Mip2; Scyb; MIP-2; Scyb2; MIP-2a; Mgsa-b; CINC-2a
UniProt Protein Name
C-X-C motif chemokine 2
UniProt Synonym Protein Names
Macrophage inflammatory protein 2; MIP2
UniProt Gene Name
Cxcl2
UniProt Synonym Gene Names
Mip-2; Mip2; Scyb2; MIP2
UniProt Entry Name
CXCL2_MOUSE
NCBI Protein Information
C-X-C motif chemokine 2

UniProt Comments for MIP2

Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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