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Nesfatin-1 (NUCB2) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844465

Background: Nesfatin-1, a polypeptide produced by cleavage of the NEFA/nucleobindin-2 (NUCB2), is a secreted protein, expressed in the appetite-control hypothalamic nuclei. Nesfatin is involved in the regulation of the feeding behavior. Intracerebroventicular… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Nesfatin-1 (Nucb2), Active Protein
Full Product Name
Nesfatin-1, mouse recombinant
Product Gene Name
Product Synonym Names
Nesfatin 1; Nucleobindin-2; DNA-binding protein NEFA; Prepronefastin
Host
E Coli
Form/Format
Sterile filtered and lyophilized from PBS
Appearance: Lyophilized protein
Purity/Purification
>=95%
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
8.0 kDa
3D Structure
ModBase 3D Structure for P81117
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Solubility/Reconstitution Instructions
Reconstitute with sterile H?O to a concentration of 0.1-1 mg/ml. Further dilutions should be made with medium containing 0.2% BSA.
Endotoxin Level
<0.1 ng/mug
Biological Activity
Not available at this time
Handling
Centrifuge the vial prior to opening.
Applications Tested/Suitable for Nucb2 active protein
SDS-PAGE; HPLC

Other Notes

Small volumes of Nucb2 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nucb2 purchase

MBS844465 is an active protein targeting Nucb2. Also known as Nesfatin-1, mouse recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Nucb2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nucleobindin-2
NCBI Official Synonym Full Names
nucleobindin 2
NCBI Official Symbol
Nucb2
NCBI Official Synonym Symbols
Nefa; Calnuc; AI607786; Nesfatin-1
UniProt Protein Name
Nucleobindin-2
UniProt Synonym Protein Names
DNA-binding protein NEFA; Prepronesfatin
Protein Family
UniProt Gene Name
Nucb2
UniProt Synonym Gene Names
Nefa
UniProt Entry Name
NUCB2_MOUSE
NCBI Protein Information
nucleobindin-2

UniProt Comments for Nucb2

NUCB2: Calcium-binding protein. May have a role in calcium homeostasis. Belongs to the nucleobindin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Vesicle

Cellular Component: Golgi apparatus; nuclear outer membrane; extracellular space; membrane; cell; endoplasmic reticulum; cytoplasm; ER-Golgi intermediate compartment; extracellular region; nucleus; Golgi medial cisterna

Molecular Function: DNA binding; metal ion binding; calcium ion binding; tumor necrosis factor receptor binding

Biological Process: cellular calcium ion homeostasis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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