Mouse Recombinant GSTM1 Active Protein – Cat# MBS844527

GSTM 1 (GSTM1) Mouse Recombinant Active Protein

Name: GSTM1 Active Protein; GSTM 1; Mouse Recombinant; MyBioSource
Brand: MyBioSource
SKU: MBS844527
Price: 430 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844527

Background: GSTM1 is a glutathione S-transferase that belongs to the mu class. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

GSTM 1 (GSTM1), Active Protein

Full Product Name

Mouse Recombinant GSTM 1

Product Gene Name

GSTM1 active protein

Product Synonym Names

Glutathione S-transferase Mu 1; GST class-mu1; GST 1-1; pmGT10.; Mouse Recombinant GSTM 1

Sequence

MPMILGYWNV RGLTHPIRML LEYTDSSYDE KRYTMGDAPD FDRSQWLNEK FKLGLDFPNL PYLIDGSHKI TQSNAILRYL ARKHHLDGET EEERIRADIV ENQVMDTRMQ LIMLCYNPDF EKQKPEFLKT IPEKMKLYSE FLGKRPWFAG DKVTYVDFLA YDILDQYRMF EPKCLDAFPN LRDFLARFEG LKKISAYMKS SRYIATPIFS KMAHWSNK

Host

E Coli

Form/Format

1 mg/ml solution in PBS (pH 7.4) containing 5 mM Glutathione
Appearance: Liquid

Purity/Purification

>=95%

Concentration

1 mg/ml (lot specific)

Preparation and Storage

At -80 degree C
Shelf Life: 12 months

Molecular Weight

25.9 kDa

3D Structure

ModBase 3D Structure for P10649

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Endotoxin Level

< 1.0 EU per 1 mug of protein (determined by LAL method).

Biological Activity

Specific activity is 3 units/mg.

Unit Definition

Specific activity is defined as the amount of enzyme that conjugates 1.0 u mole of 1-chloro-2, 4-dinitrobenzene (CDNB) with reduced glutathione per minute at pH 6.5 at 25 degree C.

Handling

Centrifuge the vial prior to opening.

Product Categories/Family for GSTM1 active protein

Proteins and Enzymes; Proteins and Enzymes (A-Z)

Applications Tested/Suitable for GSTM1 active protein

SDS-PAGE

Other Notes

Small volumes of GSTM1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSTM1 purchase

MBS844527 is an active protein targeting GSTM1. Also known as Mouse Recombinant GSTM 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GSTM1. It may not necessarily be applicable to this product.

NCBI GI #

6754084

NCBI GeneID

14862

NCBI Accession #

NP_034488.1

UniProt Primary Accession #

P10649

UniProt Secondary Accession #

Q58ET5; A2AE90

UniProt Related Accession #

P10649

GenBank Nucleotide #

NM_010358.5

NCBI Official Full Name

glutathione S-transferase Mu 1

NCBI Official Synonym Full Names

glutathione S-transferase, mu 1

NCBI Official Symbol

Gstm1

NCBI Official Synonym Symbols

Gstb1; Gstb-1

UniProt Protein Name

Glutathione S-transferase Mu 1

UniProt Synonym Protein Names

GST 1-1; GST class-mu 1; Glutathione S-transferase GT8.7; pmGT10

Protein Family

Glutathione S-transferase

UniProt Gene Name

Gstm1

UniProt Entry Name

GSTM1_MOUSE

NCBI Protein Information

glutathione S-transferase Mu 1

UniProt Comments for GSTM1

GSTM1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Mu family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.5.1.18; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450; Other Amino Acids Metabolism - glutathione

Cellular Component: protein complex; cytoplasm; extracellular region; myelin sheath

Molecular Function: transferase activity; protein binding; protein homodimerization activity; glutathione transferase activity; protein heterodimerization activity; nickel ion binding; steroid binding

Biological Process: glutathione metabolic process; metabolic process

Research Articles on GSTM1

1. Six proteins were regulated at both basal and inducible levels exhibiting the largest dynamic range of Nrf2 regulation: cytochrome CYP2A5, GSTM3, GSTM1, ENTPD5,UDPGDH, and EPHX1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GSTM1 active protein

Reference Product	PubMed Publications
Gstt1 active protein	>2091 publications with GSTM1 and Gstt1
Cyp1a1 active protein	>644 publications with GSTM1 and Cyp1a1
Cyp2e1 active protein	>272 publications with GSTM1 and Cyp2e1
Ephx1 active protein	>158 publications with GSTM1 and Ephx1
Gstm3 active protein	>132 publications with GSTM1 and Gstm3
Cyp1b1 active protein	>78 publications with GSTM1 and Cyp1b1
Cyp1a2 active protein	>72 publications with GSTM1 and Cyp1a2
Gstm2 active protein	>34 publications with GSTM1 and Gstm2
Gstt2 active protein	>21 publications with GSTM1 and Gstt2
Mgst1 active protein	>3 publications with GSTM1 and Mgst1

Pathways associated with GSTM1 active protein

Products by Pathway	Pathway Diagram
Aflatoxin B1 Metabolism Pathway antibodies	Aflatoxin B1 Metabolism Pathway Diagram
Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
Chemical Carcinogenesis Pathway antibodies	Chemical Carcinogenesis Pathway Diagram
Chemical Carcinogenesis Pathway antibodies	Chemical Carcinogenesis Pathway Diagram
Drug Metabolism - Cytochrome P450 Pathway antibodies	Drug Metabolism - Cytochrome P450 Pathway Diagram
Drug Metabolism - Cytochrome P450 Pathway antibodies	Drug Metabolism - Cytochrome P450 Pathway Diagram
Estrogen Metabolism Pathway antibodies	Estrogen Metabolism Pathway Diagram
Glutathione Conjugation Pathway antibodies	Glutathione Conjugation Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram

Diseases associated with GSTM1 active protein

Disease Name	Pubmed Publications
Disease Susceptibility Antibodies	>1293 publications with GSTM1 and Disease Susceptibility
Genetic Predisposition to Disease Antibodies	>1148 publications with GSTM1 and Genetic Predisposition to Disease
Lung Neoplasms Antibodies	>323 publications with GSTM1 and Lung Neoplasms
Carcinoma, Squamous Cell Antibodies	>227 publications with GSTM1 and Carcinoma, Squamous Cell
Skin Diseases Antibodies	>214 publications with GSTM1 and Skin Diseases
Colorectal Neoplasms Antibodies	>154 publications with GSTM1 and Colorectal Neoplasms
Leukemia Antibodies	>148 publications with GSTM1 and Leukemia
Liver Diseases Antibodies	>138 publications with GSTM1 and Liver Diseases
Urinary Bladder Neoplasms Antibodies	>131 publications with GSTM1 and Urinary Bladder Neoplasms
Chromosome Aberrations Antibodies	>128 publications with GSTM1 and Chromosome Aberrations

Organs/Tissues associated with GSTM1 active protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>865 publications with GSTM1 and Blood
Lung Antibodies	>462 publications with GSTM1 and Lung
Liver Antibodies	>208 publications with GSTM1 and Liver
Bladder Antibodies	>176 publications with GSTM1 and Bladder
Stomach Antibodies	>91 publications with GSTM1 and Stomach
Prostate Antibodies	>85 publications with GSTM1 and Prostate
Skin Antibodies	>77 publications with GSTM1 and Skin
Kidney Antibodies	>66 publications with GSTM1 and Kidney
Brain Antibodies	>57 publications with GSTM1 and Brain
Heart Antibodies	>47 publications with GSTM1 and Heart