Galectin-7 (LGALS7) Active Protein

Name: LGALS7 Active Protein; Galectin-7; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS844730
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844730

Background: Galectin-7 belongs to growing family of evolutionary conserved animal lectins. Galectins consists of beta-galactoside binding lectins that contain homologous carbohydrate recognition domains (CRDs). Galectin has the ability to induce apoptosis of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Galectin-7 (LGALS7), Active Protein

Full Product Name

Galectin-7, human recombinant

Product Gene Name

LGALS7 active protein

Product Synonym Names

Galactein 7; Galectin7; Gal-7; HKL-14; PI7; p53-induced gene 1 protein

Host

E Coli

Form/Format

Sterile filtered and lyophilized with no additives
Appearance: Lyophilized protein

Purity/Purification

>=98%

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

15.4 kDa

OMIM

600615

3D Structure

ModBase 3D Structure for P47929

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Solubility/Reconstitution Instructions

Reconstitute in H?O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers

Endotoxin Level

<0.1 ng/mug

Biological Activity

Measured by its ability to agglutinate human red blood cells. The ED?? for the effect is typically 1-7 ug/ml.

Results

1-7 mg/ml.

Handling

Centrifuge the vial prior to opening.

Applications Tested/Suitable for LGALS7 active protein

SDS-PAGE; HPLC

Other Notes

Small volumes of LGALS7 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LGALS7 purchase

MBS844730 is an active protein targeting LGALS7. Also known as Galectin-7, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for LGALS7. It may not necessarily be applicable to this product.

NCBI GI #

109948279

NCBI GeneID

653499

NCBI Accession #

NP_001035972.1

UniProt Primary Accession #

P47929

UniProt Secondary Accession #

Q6IB87

UniProt Related Accession #

P47929

GenBank Nucleotide #

NM_001042507.3

NCBI Official Full Name

galectin-7

NCBI Official Synonym Full Names

lectin, galactoside-binding, soluble, 7B

NCBI Official Symbol

LGALS7B

NCBI Official Synonym Symbols

PI7; GAL7; Gal-7; HKL-14; LGALS7

UniProt Protein Name

Galectin-7

UniProt Synonym Protein Names

HKL-14; PI7; p53-induced gene 1 protein

Protein Family

Galectin

UniProt Gene Name

LGALS7

UniProt Synonym Gene Names

PIG1; Gal-7

UniProt Entry Name

LEG7_HUMAN

NCBI Protein Information

galectin-7

NCBI Summary for LGALS7

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]

UniProt Comments for LGALS7

LGALS7B: Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.

Protein type: Cell adhesion; Apoptosis

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: extracellular space; cytoplasm; nucleus

Molecular Function: carbohydrate binding

Biological Process: heterophilic cell adhesion; apoptosis

Research Articles on LGALS7

1. serum concentration was significantly elevated in women (weeks 10-12 and 17-20) who subsequently developed pre-eclampsia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with LGALS7 active protein

Disease Name	Pubmed Publications
Skin Diseases Antibodies	>1 publications with LGALS7 and Skin Diseases
Precancerous Conditions Antibodies	>1 publications with LGALS7 and Precancerous Conditions
Inflammation Antibodies	>1 publications with LGALS7 and Inflammation

Organs/Tissues associated with LGALS7 active protein

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1 publications with LGALS7 and Skin