• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CD244 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844804

Background: CD244 (Natural Killer Cell Receptor 2B4), also known as Cluster of Differentiation 244, contains 2 Ig-like (immunoglobulin-like) domains. A role for the subtypes of CD2 Ig superfamily receptors has been recently demonstrated in eosinophilic… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
CD244, Recombinant Protein
Full Product Name
CD244, human recombinant
Product Gene Name
CD244 recombinant protein
Product Synonym Names
CD244 molecule; natural killer cell receptor 2B4; 2B4; NAIL; NKR2B4; Nmrk; SLAMF4
Sequence
MGSSHHHHHH SSGLVPRGSH MGSH GKGCQG SADHVVSISG VPLQLQPNSI QTKVDSIAWK KLLPSQNGFH HILKWENGSL PSNTSNDRFS FIVKNLSLLI KAAQQQDSGL YCLEVTSISG KVQTATFQVF VFDKVEKPRL QGQGKILDRG RCQVALSCLV SRDGNVSYAW YRGSKLIQTA GNLTYLDEEV DINGTHTYTC NVSNPVSWES HTLNLTQDCQ NAHQEFRFWP
Host
E Coli
Form/Format
0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea.
Appearance: Liquid
Purity/Purification
>=85%
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
At -80 degree C
Shelf Life: 12 months
Molecular Weight
25.5 kDa (230 aa, 19-224 aa + His Tag), confirmed by MALDI-TOF.
OMIM
605554
3D Structure
ModBase 3D Structure for Q9BZW8
Handling
Centrifuge the vial prior to opening.

Product Categories/Family for CD244 recombinant protein

Cytokines; Growth Factors & Hormones; CDsCytokines; Growth Factors & Hormones; Cytokines & Growth Factors (A-Z) Proteins and Enzymes; Cytokines; Growth Factors & Hormones; CDsProteins and Enzymes; Cytokines; Growth Factors & Hormones; Cytokines & Growth F
Applications Tested/Suitable for CD244 recombinant protein
SDS-PAGE

Testing Data of CD244 recombinant protein

CD244 Recombinant Protein – Cat# MBS844804

Other Notes

Small volumes of CD244 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD244 purchase

MBS844804 is a recombinant protein targeting CD244. Also known as CD244, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CD244. It may not necessarily be applicable to this product.

NCBI GI #
262263435
NCBI GeneID
51744
NCBI Accession #
NP_001160135.1
UniProt Primary Accession #
Q9BZW8
UniProt Secondary Accession #
Q5VYI2; Q5VYI6; Q5VYI7; Q96T47; Q9NQD2; Q9NQD3; Q9Y288
UniProt Related Accession #
Q9BZW8
GenBank Nucleotide #
NM_001166663.1
NCBI Official Full Name
natural killer cell receptor 2B4 isoform 2
NCBI Official Synonym Full Names
CD244 molecule, natural killer cell receptor 2B4
NCBI Official Symbol
CD244
NCBI Official Synonym Symbols
2B4; NAIL; Nmrk; NKR2B4; SLAMF4
UniProt Protein Name
Natural killer cell receptor 2B4
UniProt Synonym Protein Names
NK cell activation-inducing ligand; NAIL; NK cell type I receptor protein 2B4; NKR2B4; h2B4; SLAM family member 4; SLAMF4; Signaling lymphocytic activation molecule 4; CD_antigen: CD244
Protein Family
Natural killer cell receptor
UniProt Gene Name
CD244
UniProt Synonym Gene Names
2B4; NAIL; NKR2B4; h2B4; SLAMF4
UniProt Entry Name
CD244_HUMAN
NCBI Protein Information
natural killer cell receptor 2B4

NCBI Summary for CD244

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Show more

UniProt Comments for CD244

CD244: Modulate other receptor-ligand interactions to enhance leukocyte activation. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: plasma membrane; integral to membrane; external side of plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: signal transduction; blood coagulation; leukocyte migration

Disease: Rheumatoid Arthritis
Show more

Research Articles on CD244

1. this study investigates the structural requirements for the recruitment of the human-activating NK-cell receptors NKG2D and 2B4 to detergent-resistant membrane fractions in the murine BA/F3 cell line and in the human NK-cell line NKL.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CD244 recombinant protein

 Reference Product  PubMed Publications
 CD48 recombinant protein  >102 publications with CD244 and CD48
 SH2D1A recombinant protein  >47 publications with CD244 and SH2D1A
 FYN recombinant protein  >9 publications with CD244 and FYN
 LAT recombinant protein  >4 publications with CD244 and LAT
 SH2D1B recombinant protein  >4 publications with CD244 and SH2D1B
 SLAMF6 recombinant protein  >3 publications with CD244 and SLAMF6
 SH3BP2 recombinant protein  >2 publications with CD244 and SH3BP2
 ARHGEF7 recombinant protein  >1 publications with CD244 and ARHGEF7
 CD247 recombinant protein  >1 publications with CD244 and CD247

Pathways associated with CD244 recombinant protein

 Products by Pathway  Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram

Diseases associated with CD244 recombinant protein

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >15 publications with CD244 and Liver Diseases
 Inflammation Antibodies  >15 publications with CD244 and Inflammation
 Necrosis Antibodies  >14 publications with CD244 and Necrosis
 Disease Models, Animal Antibodies  >12 publications with CD244 and Disease Models, Animal
 Arthritis, Rheumatoid Antibodies  >9 publications with CD244 and Arthritis, Rheumatoid
 Hematologic Diseases Antibodies  >8 publications with CD244 and Hematologic Diseases
 Nervous System Diseases Antibodies  >8 publications with CD244 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >5 publications with CD244 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >3 publications with CD244 and Breast Neoplasms
 Ovarian Diseases Antibodies  >3 publications with CD244 and Ovarian Diseases

Organs/Tissues associated with CD244 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >258 publications with CD244 and Blood
 Liver Antibodies  >14 publications with CD244 and Liver
 Spleen Antibodies  >11 publications with CD244 and Spleen
 Placenta Antibodies  >4 publications with CD244 and Placenta
 Thymus Antibodies  >4 publications with CD244 and Thymus
 Uterus Antibodies  >3 publications with CD244 and Uterus
 Brain Antibodies  >3 publications with CD244 and Brain
 Intestine Antibodies  >2 publications with CD244 and Intestine
 Connective Tissue Antibodies  >1 publications with CD244 and Connective Tissue
 Testis Antibodies  >1 publications with CD244 and Testis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000