NEK7 Recombinant Protein

Name: NEK7 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS844957
Price: 430 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS844957

Background: Nek7 is a member of the NIMA (never in mitosis, gene A) family of serine/threonine kinases. In contrast to the other documented NIMA-related kinases, Nek7 harbor its catalytic domain in the C-terminus of the protein. Immunofluorescence studies… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

NEK7, Recombinant Protein

Full Product Name

NEK7, Active

Product Gene Name

NEK7 recombinant protein

Product Synonym Names

NEK; Serine/threonine-protein kinase Nek6; Serine/threonine-protein kinase Nek6; Never in mitosis A-related kinase 6; NimA-related protein kinase 6; Protein kinase SID6-1512; NEK; Serine/threonine-protein kinase Nek7

Host

Baculovirus (Sf9 insect cells)

Form/Format

Recombinant proteins in storage buffer (50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol).
Appearance: Liquid

Purity/Purification

>=90%

Concentration

5ug/50 ul (lot specific)

Preparation and Storage

At -80 degree C
Shelf Life: 12 months

Molecular Weight

63.0 kDa

OMIM

606848

Activity (Specifications/test method)

221 nmol phosphate incorporated into beta-casein per minute per mg protein at 30 degree C for 15 minutes using a final concentration of 50 uM ATP (0.83 uCi/assay).

Handling

Centrifuge the vial prior to opening.

Applications Tested/Suitable for NEK7 recombinant protein

SDS-PAGE; HPLC

Other Notes

Small volumes of NEK7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NEK7 purchase

MBS844957 is a recombinant protein targeting NEK7. Also known as NEK7, Active. Host: Baculovirus (Sf9 insect cells).

Additional Details

NCBI/Uniprot data below describe general gene information for NEK7. It may not necessarily be applicable to this product.

NCBI GI #

215820653

NCBI GeneID

140609

NCBI Accession #

NP_598001.1

UniProt Secondary Accession #

A6NGT8

UniProt Related Accession #

Q8TDX7

GenBank Nucleotide #

NM_133494

NCBI Official Full Name

Homo sapiens NIMA-related kinase 7 (NEK7), mRNA

NCBI Official Synonym Full Names

NIMA-related kinase 7

NCBI Official Symbol

NEK7

UniProt Protein Name

Serine/threonine-protein kinase Nek7

UniProt Synonym Protein Names

Never in mitosis A-related kinase 7; NimA-related protein kinase 7

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

NEK7

UniProt Synonym Gene Names

NimA-related protein kinase 7

UniProt Entry Name

NEK7_HUMAN

NCBI Protein Information

serine/threonine-protein kinase Nek7

NCBI Summary for NEK7

NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002]

UniProt Comments for NEK7

NEK7: a protein kinase of the NEK family. Phosphorylates and activates p70S6 kinase.

Protein type: Protein kinase, Other; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Other group; NEK family

Chromosomal Location of Human Ortholog: 1q31.3

Cellular Component: nucleoplasm; spindle pole; microtubule; cytoplasm; microtubule organizing center

Molecular Function: protein serine/threonine kinase activity; metal ion binding; ATP binding

Biological Process: regulation of mitotic cell cycle; regulation of signal transduction; cytokinesis; spindle assembly; protein amino acid phosphorylation

Research Articles on NEK7

1. Nek7, was significantly associated with certain clinicopathologic indices in gallbladder carcinoma

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.