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OSTF1 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845184

Background: Osteoclast-stimulating factor-1 (OSTF1) is an intracellular protein produced by osteoclasts that indirectly induces osteoclast (OCL) formation and bone resorption. OSTF1 is highly expressed in OCL and contains structural domains such as SH3 and… More details

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Sample Manual Insert View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
OSTF1, Recombinant Protein
Full Product Name
OSTF1, human recombinant
Product Gene Name
Product Synonym Names
Osteoclast stimulating factor 1; SH3P2; OSF
Sequence
MSKPPPKPVK PGEGGQVKVF RALYTFEPRT PDELYFEEGD IIYITDMSDT NWWKGTSKGR TGLIPSNYVA EQAESIDNPL HEAAKRGNLS WLRECLDNRV GVNGLDKAGS TALYWACHGG HKDIVEMLFT QPNIELNQQN KLGDTALHAA AWKGYADIVQ LFLAKGARTD LRNIEKKLAF DMATNAACAS LLKKKQGTDA VRTLSNAEDY LDDEDSDLEH HHHHH
Host
E Coli
Form/Format
1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 0.5 mM DTT.
Appearance: Liquid
Purity/Purification
>=95%
Concentration
1 mg/ml (lot specific)
Preparation and Storage
At -80 degree C
Shelf Life: 12 months
Molecular Weight
25.1 kDa (225 aa, 1-217 aa + His Tag), confirmed by MALDI-TOF. (MW on SDS-PAGE shifts up)
OMIM
610180
3D Structure
ModBase 3D Structure for Q92882
Endotoxin Level
< 1.0 EU per 1 microgram of protein
Handling
Centrifuge the vial prior to opening.
Applications Tested/Suitable for OSTF1 recombinant protein
SDS-PAGE

Other Notes

Small volumes of OSTF1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OSTF1 purchase

MBS845184 is a recombinant protein targeting OSTF1. Also known as OSTF1, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for OSTF1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
osteoclast-stimulating factor 1
NCBI Official Synonym Full Names
osteoclast stimulating factor 1
NCBI Official Symbol
OSTF1
NCBI Official Synonym Symbols
OSF; SH3P2; bA235O14.1
UniProt Protein Name
Osteoclast-stimulating factor 1
UniProt Gene Name
OSTF1
UniProt Entry Name
OSTF1_HUMAN
NCBI Protein Information
osteoclast-stimulating factor 1

NCBI Summary for OSTF1

Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).[supplied by OMIM, Mar 2008]

UniProt Comments for OSTF1

OSTF1: Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.

Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 9q13-q21.2

Cellular Component: cytoplasm; intracellular

Molecular Function: protein binding; SH3 domain binding

Biological Process: ossification; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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