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FGF-22 (FGF22) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845230

Background: Fibroblast Growth Factor-22 stimulates the proliferation and activation of cells that express FGF receptor. The human FGF-22 is a 17.3 kDa protein containing 149 amino acid residues. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
FGF-22 (FGF22), Recombinant Protein
Full Product Name
FGF-22, human recombinant
Product Gene Name
Product Synonym Names
FGF22; Fibroblast growth factor 23; Fibroblast growth factor 22; FGF-22.
Host
E Coli
Form/Format
Sterile filtered and lyophilized with no additives
Appearance: Lyophilized protein
Purity/Purification
>=97%
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
17.3 kDa
OMIM
605831
3D Structure
ModBase 3D Structure for Q9HCT0
Solubility/Reconstitution Instructions
Reconstitute in sterile H?O to a concentration no less than 100 mug/ml of FGF-22.
Endotoxin Level
<0.1 ng/mug
Handling
Centrifuge the vial prior to opening.
Applications Tested/Suitable for FGF22 recombinant protein
SDS-PAGE; HPLC

Other Notes

Small volumes of FGF22 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGF22 purchase

MBS845230 is a recombinant protein targeting FGF22. Also known as FGF-22, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for FGF22. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fibroblast growth factor 22 isoform 1
NCBI Official Synonym Full Names
fibroblast growth factor 22
NCBI Official Symbol
FGF22
UniProt Protein Name
Fibroblast growth factor 22
UniProt Gene Name
FGF22
UniProt Synonym Gene Names
FGF-22
UniProt Entry Name
FGF22_HUMAN
NCBI Protein Information
fibroblast growth factor 22

NCBI Summary for FGF22

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
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UniProt Comments for FGF22

FGF22: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development. Belongs to the heparin-binding growth factors family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: Golgi apparatus; extracellular space; cell surface; nucleolus; extracellular region

Molecular Function: growth factor activity; fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; insulin receptor signaling pathway; innate immune response; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with FGF22 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with FGF22 and Brain
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