SCGB1A1 Recombinant Protein – Cat# MBS845273

Uteroglobin (SCGB1A1) Recombinant Protein

Name: SCGB1A1 Recombinant Protein; Uteroglobin; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS845273
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845273

Background: Uteroglobin, a member of the Secretoglobin superfamily, also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Uteroglobin (SCGB1A1), Recombinant Protein

Full Product Name

Uteroglobin, human recombinant

Product Gene Name

SCGB1A1 recombinant protein

Product Synonym Names

Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; Secretoglobin family 1A member 1; Urinary protein 1; UP-1; UP1; Urine protein 1

Sequence

MEICPSFQRV IETLLMDTPS SYEAAMELFS PDQDMREAGA QLKKLVDTLP QKPRESIIKL MEKIAQSSLC N

Host

E Coli

Form/Format

Sterile filtered through a 0.2 micron filter. Lyophilized from 1 X PBS.
Appearance: Lyophilized powder

Purity/Purification

>=98%

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

8.0 kDa

OMIM

192020

3D Structure

ModBase 3D Structure for P11684

Solubility/Reconstitution Instructions

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8 degree C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20 degree C to -80 degree C.

Endotoxin Level

< 0.1 ng/mug of protein (<1EU/mug).

Handling

Centrifuge the vial prior to opening.

Product Categories/Family for SCGB1A1 recombinant protein

Cytokines; Growth Factors & Hormones; Cytokines & Growth Factors (A-Z) Proteins and Enzymes; Cytokines; Growth Factors & Hormones; Cytokines & Growth Factors (A-Z) Proteins and Enzymes; Proteins and Enzymes (A-Z) Proteins and Enzymes; Animal-Free Origin

Applications Tested/Suitable for SCGB1A1 recombinant protein

SDS-PAGE; HPLC

Other Notes

Small volumes of SCGB1A1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCGB1A1 purchase

MBS845273 is a recombinant protein targeting SCGB1A1. Also known as Uteroglobin, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SCGB1A1. It may not necessarily be applicable to this product.

NCBI GI #

4507809

NCBI GeneID

7356

NCBI Accession #

NP_003348.1

UniProt Primary Accession #

P11684

UniProt Secondary Accession #

Q6FHH3; Q9UCM2; Q9UCM4; B2R5F2

UniProt Related Accession #

P11684

GenBank Nucleotide #

NM_003357.4

NCBI Official Full Name

uteroglobin

NCBI Official Synonym Full Names

secretoglobin, family 1A, member 1 (uteroglobin)

NCBI Official Symbol

SCGB1A1

NCBI Official Synonym Symbols

UGB; UP1; CC10; CC16; CCSP; UP-1; CCPBP

UniProt Protein Name

Uteroglobin

UniProt Synonym Protein Names

Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; Secretoglobin family 1A member 1; Urinary protein 1; UP-1; UP1; Urine protein 1

Protein Family

Uteroglobin

UniProt Gene Name

SCGB1A1

UniProt Synonym Gene Names

CC10; CCSP; UGB; CCPBP; CC10; UP-1; UP1; Urine protein 1

UniProt Entry Name

UTER_HUMAN

NCBI Protein Information

uteroglobin

NCBI Summary for SCGB1A1

This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010]

UniProt Comments for SCGB1A1

SCGB1A1: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Belongs to the secretoglobin family.

Protein type: Inhibitor; Secreted, signal peptide; Secreted; Cell cycle regulation

Chromosomal Location of Human Ortholog: 11q12.3

Cellular Component: extracellular space; rough endoplasmic reticulum; nuclear envelope; secretory granule

Molecular Function: protein binding; phospholipase A2 inhibitor activity

Biological Process: response to drug; negative regulation of interleukin-4 production; response to glucocorticoid stimulus; response to lipopolysaccharide; negative regulation of transcription from RNA polymerase II promoter; female pregnancy; regulation of mRNA stability; signal transduction; response to xenobiotic stimulus; negative regulation of interleukin-13 production; response to silicon dioxide; negative regulation of T cell proliferation; response to ozone; negative regulation of interferon-gamma production; response to cytokine stimulus; regulation of inflammatory response; negative regulation of catalytic activity; negative regulation of interleukin-5 production; embryo implantation

Disease: Asthma, Susceptibility To

Research Articles on SCGB1A1

1. A meta-analysis indicated that the CC16 gene A38G polymorphism is not associated with the risk of asthma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SCGB1A1 recombinant protein

Reference Product	PubMed Publications
TNF recombinant protein	>23 publications with SCGB1A1 and TNF
FOXA2 recombinant protein	>11 publications with SCGB1A1 and FOXA2
FOXA1 recombinant protein	>10 publications with SCGB1A1 and FOXA1
ADSS recombinant protein	>3 publications with SCGB1A1 and ADSS
SPDEF recombinant protein	>2 publications with SCGB1A1 and SPDEF

Diseases associated with SCGB1A1 recombinant protein

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>301 publications with SCGB1A1 and Lung Diseases
Inflammation Antibodies	>143 publications with SCGB1A1 and Inflammation
Lung Injury Antibodies	>134 publications with SCGB1A1 and Lung Injury
Asthma Antibodies	>80 publications with SCGB1A1 and Asthma
Lung Neoplasms Antibodies	>58 publications with SCGB1A1 and Lung Neoplasms
Carcinoma Antibodies	>43 publications with SCGB1A1 and Carcinoma
Respiration Disorders Antibodies	>41 publications with SCGB1A1 and Respiration Disorders
Pneumonia Antibodies	>39 publications with SCGB1A1 and Pneumonia
Adenocarcinoma Antibodies	>35 publications with SCGB1A1 and Adenocarcinoma
Necrosis Antibodies	>34 publications with SCGB1A1 and Necrosis

Organs/Tissues associated with SCGB1A1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>481 publications with SCGB1A1 and Lung
Trachea Antibodies	>40 publications with SCGB1A1 and Trachea
Thyroid Antibodies	>29 publications with SCGB1A1 and Thyroid
Bone Marrow Antibodies	>11 publications with SCGB1A1 and Bone Marrow
Mouth Antibodies	>7 publications with SCGB1A1 and Mouth
Intestine Antibodies	>7 publications with SCGB1A1 and Intestine
Prostate Antibodies	>5 publications with SCGB1A1 and Prostate
Connective Tissue Antibodies	>3 publications with SCGB1A1 and Connective Tissue
Pharynx Antibodies	>3 publications with SCGB1A1 and Pharynx
Pancreas Antibodies	>3 publications with SCGB1A1 and Pancreas