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Il-22 (IL22) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845284

Background: Murine Interleukin-22 (IL-22), also known as T cell-derived inducible factor (ILTIF), is a cytokine that is structurally related to IL-10. Studies have shown that IL-22 induces acute-phase reactants in vitro and in vivo, suggesting that the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IL-22 (IL22), Active Protein
Full Product Name
IL-22, murine recombinant
Product Gene Name
Product Synonym Names
IL-TIF; TIFa; IL-10-related T-cell-derived-inducible factor; IL-22; ILTIF; IL-D110; zcyto18; MGC79382; MGC79384; TIFIL-23
Host
E Coli
Form/Format
Lyophilized from 1X PBS Solution
Appearance: Lyophilized protein
Purity/Purification
>=97%
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
33.4 kDa
3D Structure
ModBase 3D Structure for Q9JJY9
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Solubility/Reconstitution Instructions
Reconstitute in H?O to a concentration of 0.1 to 1.0 mg/ml. This solution can then be stored at 4 degree C for 1 week or -20 degree C for future use. For long term storage, it is recommended to add a carrier protein (e.g., 0.1% BSA). Avoid repeating freeze/thaw cycles.
Endotoxin Level
<0.1 ng/mug
Biological Activity
Recombinant murine IL-22 is fully biologically active when compared to a standard. The ED?? as determined by its ability to induce IL-10 secretion in Colo205 cells is less than 0.5 ng/ml, corresponding to a specific activity of 2 x 10 IU/mg.
Results
0.5 ng/ml
Handling
Centrifuge the vial prior to opening.
Applications Tested/Suitable for IL22 active protein
SDS-PAGE; HPLC

Other Notes

Small volumes of IL22 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL22 purchase

MBS845284 is an active protein targeting IL22. Also known as IL-22, murine recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for IL22. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-22
NCBI Official Synonym Full Names
interleukin 22
NCBI Official Symbol
Il22
NCBI Official Synonym Symbols
IL-22; Iltif; IL-22a; ILTIFa
UniProt Protein Name
Interleukin-22
UniProt Synonym Protein Names
IL-10-related T-cell-derived-inducible factor; IL-TIF; IL-TIF alpha; Interleukin-22a; IL-22a
Protein Family
UniProt Gene Name
Il22
UniProt Synonym Gene Names
Il22a; Iltif; Iltifa; IL-22; IL-TIF; IL-22a
UniProt Entry Name
IL22_MOUSE
NCBI Protein Information
interleukin-22

UniProt Comments for IL22

IL22: Cytokine that contributes to the inflammatory response in vivo. Belongs to the IL-10 family.

Protein type: Secreted, signal peptide; Cytokine; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; cytokine activity

Biological Process: negative regulation of inflammatory response; regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with IL22 active protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with IL22 and Brain
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