RLN3 Recombinant Protein – Cat# MBS845372

Relaxin-3 (RLN3) Recombinant Protein

Name: RLN3 Recombinant Protein; Relaxin-3; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS845372
Price: 275 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845372

Background: Relaxin-3 (H3 relaxin, Insulin-like peptide-7, INSL7) is a secreted protein structurally related to insulin, which is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Relaxin-3 (RLN3), Recombinant Protein

Full Product Name

Relaxin-3, human recombinant

Product Gene Name

RLN3 recombinant protein

Product Synonym Names

H3 relaxin; Insulin-like peptide-7; INSL7

Sequence

A Chain: DVLAGLSSSC CKWGCSKSEI SSLC B Chain: RAAPYGVRLC GREFIRAVIF TCGGSRW

Host

E Coli

Form/Format

Sterile filtered through a 0.2 micron filter. Lyophilized with no additives
Appearance: Lyophilized powder

Purity/Purification

>=98%

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

5.5 kDa

OMIM

606855

3D Structure

ModBase 3D Structure for Q8WXF3

Solubility/Reconstitution Instructions

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8 degree C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20 degree C to -80 degree C.

Endotoxin Level

< 0.1 ng/mug of protein (<1EU/mug).

Handling

Centrifuge the vial prior to opening.

Product Categories/Family for RLN3 recombinant protein

Cytokines; Growth Factors & Hormones; Cytokines & Growth Factors (A-Z) Proteins and Enzymes; Cytokines; Growth Factors & Hormones; Cytokines & Growth Factors (A-Z) Proteins and Enzymes; Animal-Free Origin (AOF) Recombinant Proteins & EnzymesProteins and E

Applications Tested/Suitable for RLN3 recombinant protein

SDS-PAGE; HPLC

Other Notes

Small volumes of RLN3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RLN3 purchase

MBS845372 is a recombinant protein targeting RLN3. Also known as Relaxin-3, human recombinant. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RLN3. It may not necessarily be applicable to this product.

NCBI GI #

18254464

NCBI GeneID

117579

NCBI Accession #

NP_543140.1

UniProt Primary Accession #

Q8WXF3

UniProt Secondary Accession #

Q6UXW5

UniProt Related Accession #

Q8WXF3

GenBank Nucleotide #

NM_080864.3

NCBI Official Full Name

relaxin-3 preproprotein

NCBI Official Synonym Full Names

relaxin 3

NCBI Official Symbol

RLN3

NCBI Official Synonym Symbols

H3; RXN3; ZINS4; insl7

UniProt Protein Name

Relaxin-3

UniProt Synonym Protein Names

Insulin-like peptide INSL7; Insulin-like peptide 7

Protein Family

Relaxin

UniProt Gene Name

RLN3

UniProt Synonym Gene Names

INSL7; RXN3; ZINS4; Insulin-like peptide 7

UniProt Entry Name

REL3_HUMAN

NCBI Protein Information

relaxin-3

NCBI Summary for RLN3

This gene encodes a member of the relaxin family of insulin-like hormones that is expressed predominantly in the brain and plays a role in physiological processes such as stress, memory and appetite regulation. The encoded protein is a precursor that is proteolytically processed to generate a heterodimeric mature form consisting A and B chains interlinked by disulfide bonds. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]

UniProt Comments for RLN3

RLN3: May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142). Belongs to the insulin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular region

Molecular Function: protein binding; G-protein-coupled receptor binding; hormone activity

Research Articles on RLN3

1. Review of research depicts the connection of relaxin-3 with phenomena such as feeding behavior, spatial memory, sleep/wake cycle or modulation of pituitary gland hormone secretion.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RLN3 recombinant protein

Reference Product	PubMed Publications
RXFP3 recombinant protein	>33 publications with RLN3 and RXFP3
RXFP1 recombinant protein	>21 publications with RLN3 and RXFP1
RXFP4 recombinant protein	>13 publications with RLN3 and RXFP4
INSL5 recombinant protein	>11 publications with RLN3 and INSL5
INSL3 recombinant protein	>9 publications with RLN3 and INSL3
RLN1 recombinant protein	>9 publications with RLN3 and RLN1
RLN2 recombinant protein	>8 publications with RLN3 and RLN2
FOS recombinant protein	>7 publications with RLN3 and FOS
RXFP2 recombinant protein	>4 publications with RLN3 and RXFP2
INSL4 recombinant protein	>2 publications with RLN3 and INSL4

Pathways associated with RLN3 recombinant protein

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Relaxin Receptors Pathway antibodies	Relaxin Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with RLN3 recombinant protein

Disease Name	Pubmed Publications
Weight Gain Antibodies	>2 publications with RLN3 and Weight Gain
Insulin Resistance Antibodies	>1 publications with RLN3 and Insulin Resistance
Hypercholesterolemia Antibodies	>1 publications with RLN3 and Hypercholesterolemia
Hypertension Antibodies	>1 publications with RLN3 and Hypertension
Inflammation Antibodies	>1 publications with RLN3 and Inflammation

Organs/Tissues associated with RLN3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>6 publications with RLN3 and Testis