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BMP-8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845508

Polyclonal Antibody to detect BMP-8 in Human; Mouse; Rat samples.BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BMP-8, Polyclonal Antibody
Full Product Name
BMP-8 Polyclonal Antibody
Product Gene Name
Product Synonym Names
BMP8; BMP-8; BMP 8; bone morphogenetic protein 8
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Colorless liquid
100 mg (0.5 mg/ml) antigen affinity purified goat anti-BMP-8 polyclonal antibody in phosphate buffered saline (PBS); pH 7.2; containing 50% glycerol and 0.02% Thimerosal.
Purity/Purification
Affinity Purified
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C for 12 months.
The antibody solution should be gently mixed before use.
Molecular Weight
39,151 Da
OMIM
M97016 mRNA
3D Structure
ModBase 3D Structure for P34820
Immunogen
Recombinant Human BMP-8

Product Categories/Family for anti-BMP-8 antibody

Applications Tested/Suitable for anti-BMP-8 antibody
Western Blot (WB)
Application Notes for anti-BMP-8 antibody
Western Blot: 1-4 ug

Other Notes

Small volumes of anti-BMP-8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMP-8 purchase

MBS845508 is an antibody targeting BMP-8. Also known as BMP-8 Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BMP-8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
bone morphogenetic protein 8B preproprotein
NCBI Official Synonym Full Names
bone morphogenetic protein 8b
NCBI Official Symbol
BMP8B
NCBI Official Synonym Symbols
OP2; BMP8
UniProt Protein Name
Bone morphogenetic protein 8B
UniProt Synonym Protein Names
Osteogenic protein 2; OP-2
UniProt Gene Name
BMP8B
UniProt Synonym Gene Names
BMP8; BMP-8; BMP-8B; OP-2
NCBI Protein Information
bone morphogenetic protein 8B

NCBI Summary for BMP-8

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]
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UniProt Comments for BMP-8

BMP8B: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Belongs to the TGF-beta family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: extracellular space

Molecular Function: cytokine activity; transforming growth factor beta receptor binding

Biological Process: BMP signaling pathway; cell development; regulation of apoptosis; regulation of MAPKKK cascade; skeletal development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BMP-8 antibody

 Reference Product  PubMed Publications
 BMP4 antibody  >15 publications with BMP-8 and BMP4
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