IFN-alpha 2a Antibody – Rabbit Polyclonal

This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]

IFNA2: Produced by macrophages, IFN-alpha have antiviral activities. Belongs to the alpha/beta interferon family.

Protein type: Membrane protein, integral; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p21.3

Cellular Component: extracellular region; extracellular space

Molecular Function: cytokine activity; interferon-alpha/beta receptor binding; protein binding

Biological Process: apoptosis; B cell differentiation; B cell proliferation; blood coagulation; cell surface receptor linked signal transduction; cell-cell signaling; cytokine and chemokine mediated signaling pathway; defense response to virus; humoral immune response; inflammatory response; innate immune response; natural killer cell activation during immune response; negative regulation of T cell differentiation; negative regulation of transcription, DNA-dependent; negative regulation of virion penetration into host cell; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of phosphorylation; positive regulation of transcription, DNA-dependent; positive regulation of tyrosine phosphorylation of STAT protein; response to exogenous dsRNA; T cell activation during immune response