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BTLA Human Cellexp Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845601

B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein; CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor; BTLA/CD272 inhibits lymphocytes during immune… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BTLA, Active Protein
Full Product Name
Human CellExp BTLA; Human recombinant
Product Gene Name
Product Synonym Gene Name
CD272
Product Synonym Names
BTLA; CD272
Host
HEK 293 cells
Source: Human
Form/Format
Lyophilized from 0.22 mum filtered solution in PBS; pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Purity/Purification
>=92%
Preparation and Storage
Store at -20 degree C for 12 months.
Centrifuge the vial prior to opening.
Molecular Weight
38.7 kDa
OMIM
AY293286 mRNA
3D Structure
ModBase 3D Structure for Q7Z6A9
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Tag Information
This protein is fused with a human IgG1 Fc tag at C-terminus. The protein migrates as 45-50 kDa in SDS-PAGE due to glycosylation.
Endotoxin Level
< 1 EU/mug
Biological Activity
Immobilized Human HVEM, C-Twin Strep Tag at 2 ng/ml (100 ul/well), can bind Human BTLA, Fc Tag with a linear of 0.1-0.5 mug/mL.
Binding Capacity
Immobilized Human HVEM; C-Twin Strep Tag at 2 ng/ml (100 ul/well); can bind Human BTLA; Fc Tag with a linear of 0.1-0.5 mug/mL.
Reconstitution
Reconstitute in sterile PBS; pH 7.4 to a concentration of 50 mug/ml
Applications Tested/Suitable for BTLA active protein
SDS-PAGE, Functional Assay

Other Notes

Small volumes of BTLA active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BTLA purchase

MBS845601 is an active protein targeting BTLA. Also known as Human CellExp BTLA; Human recombinant. Host: HEK 293 cells
Source: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for BTLA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
B- and T-lymphocyte attenuator isoform 2
NCBI Official Synonym Full Names
B and T lymphocyte associated
NCBI Official Symbol
BTLA
NCBI Official Synonym Symbols
BTLA1; CD272
UniProt Protein Name
B- and T-lymphocyte attenuator
UniProt Synonym Protein Names
B- and T-lymphocyte-associated protein; CD_antigen: CD272
UniProt Gene Name
BTLA
NCBI Protein Information
B- and T-lymphocyte attenuator

NCBI Summary for BTLA

This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]
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UniProt Comments for BTLA

BTLA: Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: plasma membrane

Biological Process: T cell costimulation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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