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PF-4708671

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845660

PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with a Ki of 20 nM and IC50 of 160 nM. PF-4708671 prevents the S6K1-mediated phosphorylation of S6 protein in response to IGF-1 (insulin-like growth factor 1); while having no… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-4708671, Biochemical
Full Product Name
PF-4708671
Product Gene Name
PF-4708671 biochemical
Product Synonym Names
2-[[4- (5-Ethylpyrimidin-4-yl) piperazin-1-yl]methyl]-5- (trifluoromethyl)-1H-benzo[d]imidazole
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
390.41
CAS Number
1255517-76-0
Cell-Permeable
Yes
Reconstitution
DMSO (>15 mg/ml)
SMILES
CC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C(N3)C=C(C=C4)C(F)(F)F
InChi
InChI=1S/C19H21F3N6/c1-2-13-10-23-12-24-18(13)28-7-5-27(6-8-28)11-17-25-15-4-3-14(19(20,21)22)9-16(15)26-17/h3-4,9-10,12H,2,5-8,11H2,1H3,(H,25,26)
InChi Key
FBLPQCAQRNSVHB-UHFFFAOYSA-N

Structure of PF-4708671 biochemical

PF-4708671 Biochemical – Cat# MBS845660

Other Notes

Small volumes of PF-4708671 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-4708671 purchase

MBS845660 is a biochemical targeting PF-4708671.
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