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PF-05212384

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845661

PF-05212384 is a potent; selective and ATP-competitive dual inhibitor of PI 3-kinase/mTOR (IC50 values are 0.4; 1.6 and 5.4 nM for PI 3-Kalpha; mTOR and PI 3-Kgamma respectively). Exhibits selectivity over 234 other protein kinases (IC50 >10 muM).… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-05212384, Biochemical
Full Product Name
PF-05212384
Product Gene Name
PF-05212384 biochemical
Product Synonym Names
N-[4-[[4- (Dimethylamino)-1-piperidinyl]carbonyl]phenyl]-N'-[4- (4; 6-di-4-morpholinyl-1; 3; 5-triazin-2-yl) phenyl]urea; Gedatolisib; PKI-587
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
615.73
CAS Number
1197160-78-3
Cell-Permeable
Yes
Reconstitution
DMSO (~ 3 mg/ml with slight warming)
SMILES
CN(C)C1CCN(CC1)C(=O)C2=CC=C(C=C2)NC(=O)NC3=CC=C(C=C3)C4=NC(=NC(=N4)N5CCOCC5)N6CCO
InChi
InChI=1S/C32H41N9O4/c1-38(2)27-11-13-39(14-12-27)29(42)24-5-9-26(10-6-24)34-32(43)33-25-7-3-23(4-8-25)28-35-30(40-15-19-44-20-16-40)37-31(36-28)41-17-21-45-22-18-41/h3-10,27H,11-22H2,1-2H3,(H2,33,34,43)
InChi Key
DWZAEMINVBZMHQ-UHFFFAOYSA-N

Structure of PF-05212384 biochemical

PF-05212384 Biochemical – Cat# MBS845661

Other Notes

Small volumes of PF-05212384 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-05212384 purchase

MBS845661 is a biochemical targeting PF-05212384.
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