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LY-2157299

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845675

LY-2157299 is a potent and selective TGFbeta receptor I (TbetaRI) inhibitor (IC50 = 56 nM). LY-2157299 abolishes the TGFbeta induced Smad2 phosphorylation in HUVEC cells. It also shows dose dependent potentiation of VEGF or bFGF induced cell proliferation in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LY-2157299, Biochemical
Full Product Name
LY-2157299
Product Gene Name
LY-2157299 biochemical
Product Synonym Names
4-[2- (6-methylpyridin-2-yl)-5; 6-dihydro-4H-pyrrolo[1; 2-b]pyrazol-3-yl]quinoline-6-carboxamide; Galunisertib
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
369.42
CAS Number
700874-72-2
Cell-Permeable
Yes
Reconstitution
DMSO (>50 mg/ml)

Other Notes

Small volumes of LY-2157299 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY-2157299 purchase

MBS845675 is a biochemical targeting LY-2157299.
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