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PRIMA-1MET

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845685

PRIMA-1MET is a methylated derivative of PRIMA-1. Restores mutant activity p53 activity. Acts synergistically with chemotherapeutic agents to inhibit tumor cell proliferation. At 25-50 uM; it can also dose-dependently inhibit thioredoxin reductase; a key… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PRIMA-1MET, Biochemical
Full Product Name
PRIMA-1MET
Product Gene Name
PRIMA-1MET biochemical
Product Synonym Names
2- (Hydroxymethyl)-2- (methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one; APR-246
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
199.25
CAS Number
5291-32-7
Cell-Permeable
Yes
Reconstitution
DMSO (>15 mg/ml) or H2O (>15 mg/ml)

Other Notes

Small volumes of PRIMA-1MET biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRIMA-1MET purchase

MBS845685 is a biochemical targeting PRIMA-1MET.
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