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Avasimibe

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845699

Avasimibe is an orally bioavailable inhibitor of the acyl coenzyme A: cholesterol acyltransferase (ACAT) (IC50 = 60 nM). Avasimibe also inhibits major drug metabolizing enzymes such as CYP2C9 (IC50 = 2.9 uM); CYP1A2 (IC50 = 13.9 uM); and CYP2C19 (IC50 = 26.5… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Avasimibe, Biochemical
Full Product Name
Avasimibe
Product Synonym Names
[2; 6-di (propan-2-yl) phenyl] N-[2-[2; 4; 6-tri (propan-2-yl) phenyl]acetyl]sulfamate; CI-1011; PD 148515
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
501.72
Salt Form
No
CAS Number
166518-60-1
Cell-Permeable
Yes
Reconstitution
DMSO (>35 mg/ml)
SMILES
CC(C)C1=C(C(=CC=C1)C(C)C)OS(=O)(=O)NC(=O)CC2=C(C=C(C=C2C(C)C)C(C)C)C(C)C
InChi
InChI=1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31)
InChi Key
PTQXTEKSNBVPQJ-UHFFFAOYSA-N

Other Notes

Small volumes of Avasimibe biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Avasimibe purchase

MBS845699 is a biochemical targeting Avasimibe.
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