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Fosaprepitant (P-[3-[[ (2R)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845711

Fosaprepitant is a prodrug of Aprepitant that acts as a selective; high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. After biologically activated to Aprepitant; it acts as an antiemetic agent. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Fosaprepitant, Biochemical
Full Product Name
Fosaprepitant
Product Synonym Names
P-[3-[[ (2R; 3S)-2-[ (1R)-1-[3; 5-Bis (trifluoromethyl) phenyl]ethoxy]-3- (4-fluorophenyl)-4-morpholinyl]methyl]-2; 5-dihydro-5-oxo-1H-1; 2; 4-triazol-1-yl]phosphonic Acid; L 758298
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
614.41
Salt Form
No
CAS Number
172673-20-0
Cell-Permeable
Yes
Reconstitution
DMSO
SMILES
CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F
InChi
InChI=1S/C23H22F7N4O6P/c1-12(14-8-15(22(25,26)27)10-16(9-14)23(28,29)30)40-20-19(13-2-4-17(24)5-3-13)33(6-7-39-20)11-18-31-21(35)34(32-18)41(36,37)38/h2-5,8-10,12,19-20H,6-7,11H2,1H3,(H,31,32,35)(H2,36,37,38)/t12-,19+,20-/m1/s1
InChi Key
BARDROPHSZEBKC-OITMNORJSA-N

Structure of Fosaprepitant biochemical

Fosaprepitant P-[3-[[ (2R Biochemical – Cat# MBS845711

Other Notes

Small volumes of Fosaprepitant biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Fosaprepitant purchase

MBS845711 is a biochemical targeting Fosaprepitant.
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