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Dinaciclib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845719

Dinaciclib is a potent and selective cyclin-dependent kinase (CDK) inhibitor displaying selectivity for CDK1; CDK2; CDK5 and CDK9 with IC50 values of 3; 1; 1 and 4 nM respectively. It has been shown to inhibit DNA synthesis by blocking thymidine incorporation… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Dinaciclib, Biochemical
Full Product Name
Dinaciclib
Product Synonym Names
2-[ (2S)-1-[3-ethyl-7-[ (1-oxidopyridin-1-ium-3-yl) methylamino]pyrazolo[1; 5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol; SCH-727965
Form/Format
Light brown solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
396.49
Salt Form
No
Molecular Formula
C21H28N6O2
CAS Number
779353-01-4
Cell-Permeable
Yes
Reconstitution
DMSO (>20 mg/ml)
SMILES
CC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCCC4CCO
InChi
InChI=1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,1H3/t18-/m0/s1
InChi Key
PIMQWRZWLQKKBJ-SFHVURJKSA-N

Other Notes

Small volumes of Dinaciclib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dinaciclib purchase

MBS845719 is a biochemical targeting Dinaciclib.
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