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ADX-47273

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845742

ADX-47273 is a potent and selective mGluR5 receptor PAM (positive allosteric modulator); EC50 = 0.17 mum; with no effect on other mGluR subtypes. ADX-47273 elevates extracellular signal-regulated kinase and cAMP-responsive element-binding protein… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ADX-47273, Biochemical
Full Product Name
ADX-47273
Product Gene Name
Product Synonym Names
(S)- (4-fluorophenyl) (3- (3- (4-fluorophenyl)-1; 2; 4-oxadiazol-5-yl) piperidin-1-yl) methanone
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
369.37
Salt Form
No
Molecular Formula
C20H17F2N3O2
CAS Number
851881-60-2
Cell-Permeable
Yes
Reconstitution
DMSO (>30 mg/ml)
SMILES
C1CC(CN(C1)C(=O)C2=CC=C(C=C2)F)C3=NC(=NO3)C4=CC=C(C=C4)F
InChi
InChI=1S/C20H17F2N3O2/c21-16-7-3-13(4-8-16)18-23-19(27-24-18)15-2-1-11-25(12-15)20(26)14-5-9-17(22)10-6-14/h3-10,15H,1-2,11-12H2/t15-/m0/s1
InChi Key
VXQCCZHCFBHTTD-HNNXBMFYSA-N

Other Notes

Small volumes of ADX-47273 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADX-47273 purchase

MBS845742 is a biochemical targeting ADX-47273.
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