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APY-0201

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845744

APY0201 is a potent; highly selective; ATP-competitive PIKfyve inhibitor (IC50 = 5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns (3; 5) P2. Also acts as a unique small molecular IL-12/23 production inhibitor. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
APY-0201, Biochemical
Full Product Name
APY-0201
Product Gene Name
APY-0201 biochemical
Product Synonym Names
(E)-4- (5- (2- (3-methylbenzylidene) hydrazinyl)-2- (pyridin-4-yl) pyrazolo[1; 5-a]pyrimidin-7-yl) morpholine
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
413.48
Salt Form
No
Molecular Formula
C23H23N7O
CAS Number
1232221-74-7
Cell-Permeable
Yes
Reconstitution
DMSO (>30 mg/ml)
SMILES
CC1=CC=CC(=C1)C=NNC2=NC3=CC(=NN3C(=C2)N4CCOCC4)C5=CC=NC=C5
InChi
InChI=1S/C23H23N7O/c1-17-3-2-4-18(13-17)16-25-27-21-15-2
InChi Key
RFZQYGBLRIKROZ-XYGWBWBKSA-N

Structure of APY-0201 biochemical

APY-0201 Biochemical – Cat# MBS845744

Other Notes

Small volumes of APY-0201 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APY-0201 purchase

MBS845744 is a biochemical targeting APY-0201.
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