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Ku-60019 ((2R)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845752

Ku-60019 is a potent; reversible inhibitor of ATM kinase (IC50 = 6.3 nM); blocking the phosphorylation of ATM substrate proteins. It is much less effective against a panel of 229 other kinases. Ku-60019 sensitizes glioma cells to radiation and inhibits… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Ku-60019, Biochemical
Full Product Name
Ku-60019
Product Gene Name
Ku-60019 biochemical
Product Synonym Names
(2R; 6S) -2; 6-dimethyl-N-[5-[6- (4-morpholinyl) -4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl]-4-morpholineacetamide
Form/Format
Light yellow to yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
547.67
Salt Form
No
CAS Number
925701-49-1
Cell-Permeable
Yes
Reconstitution
DMSO (>10 mg/ml)
SMILES
CC1CN(CC(O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C=CC=C4C3)C5=CC(=O)C=C(O5)N6CCOCC6
InChi
InChI=1S/C30H33N3O5S/c1-19-16-32(17-20(2)37-19)18-28(35)31-23-6-7-27-22(13-23)12-21-4-3-5-25(30(21)39-27)26-14-24(34)15-29(38-26)33-8-10-36-11-9-33/h3-7,13-15,19-20H,8-12,16-18H2,1-2H3,(H,31,35)/t19-,20+
InChi Key
SCELLOWTHJGVIC-BGYRXZFFSA-N

Structure of Ku-60019 biochemical

Ku-60019 (2R Biochemical – Cat# MBS845752

Other Notes

Small volumes of Ku-60019 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ku-60019 purchase

MBS845752 is a biochemical targeting Ku-60019.
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