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UNC0379

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845768

UNC0379 is a selective; substrate-competitive inhibitor of the lysine methyltransferase SET8 (IC50 = 7.3 uM; Kd = 18.3 uM). It is selective for SET8 over 15 other methyltransferases; including G9a and GLP (IC50s = >100 uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
UNC0379, Biochemical
Full Product Name
UNC0379
Product Gene Name
UNC0379 biochemical
Product Synonym Names
6; 7-dimethoxy-2- (pyrrolidin-1-yl)-N- (5- (pyrrolidin-1-yl) pentyl) quinazolin-4-amine
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
413.56
Salt Form
No
CAS Number
1620401-82-2
Cell-Permeable
Yes
Reconstitution
DMSO (~20 mg/ml)
SMILES
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCCCCN4CCCC4)OC
InChi
InChI=1S/C23H35N5O2/c1-29-20-16-18-19(17-21(20)30-2)25-23(28-14-8-9-15-28)26-22(18)24-10-4-3-5-11-27-12-6-7-13-27/h16-17H,3-15H2,1-2H3,(H,24,25,26)
InChi Key
WEXCGGWTIDNVNT-UHFFFAOYSA-N

Structure of UNC0379 biochemical

UNC0379 Biochemical – Cat# MBS845768

Other Notes

Small volumes of UNC0379 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UNC0379 purchase

MBS845768 is a biochemical targeting UNC0379.
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