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OF-1 (4-Bromo-N- (2)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845772

OF-1 is a selective BRPF1B and BRPF2 bromodomain inhibitor (Kd values are 100 and 500 nM respectively). OF-1 displays 39-fold selectivity for BRPF1B and BRPF2 over BRD4. It increases thermal stability of full length BRPF1B at 1 uM; in the cellular thermal… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
OF-1, Biochemical
Full Product Name
OF-1
Product Gene Name
OF-1 biochemical
Product Synonym Names
4-Bromo-N- (2; 3-dihydro-6-methoxy-1; 3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methylbenzenesulfonamide
Form/Format
Beige solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
440.31
Salt Form
No
CAS Number
919973-83-4
Cell-Permeable
Yes
Reconstitution
DMSO (>8 mg/ml)
SMILES
CC1=C(C=CC(=C1)Br)S(=O)(=O)NC2=C(C=C3C(=C2)N(C(=O)N3C)C)OC
InChi
InChI=1S/C17H18BrN3O4S/c1-10-7-11(18)5-6-16(10)26(23,24)19-12-8-13-14(9-15(12)25-4)21(3)17(22)20(13)2/h5-9,19H,1-4H3
InChi Key
YUNQZQREIHWDQT-UHFFFAOYSA-N

Structure of OF-1 biochemical

OF-1 4-Bromo-N- (2 Biochemical – Cat# MBS845772

Other Notes

Small volumes of OF-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OF-1 purchase

MBS845772 is a biochemical targeting OF-1.
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